Jian Yang is a Chinese statistical geneticist and Professor of Statistical Genomics at the
University of Queensland
, mottoeng = By means of knowledge and hard work
, established =
, endowment = A$224.3 million
, budget = A$2.1 billion
, type = Public research university
, chancellor = Peter Varghese
, vice_chancellor = Deborah Terry
, city = B ...
's Institute for Molecular Bioscience, as well as an affiliated professor at the
Queensland Brain Institute
The Queensland Brain Institute (QBI) is an Australian neuroscience research institute, located in Brisbane at the St Lucia campus of The University of Queensland (UQ). Founding director Professor Perry Bartlett established the QBI in 2003 with ...
. He received the 2015
Ruth Stephens Gani Medal for his research on the "
missing heritability The "missing heritability" problem is the fact that single genetic variations cannot account for much of the heritability of diseases, behaviors, and other phenotypes. This is a problem that has significant implications for medicine, since a person ...
" of
complex trait
Complex traits, also known as quantitative traits, are traits that do not behave according to simple Mendelian inheritance laws. More specifically, their inheritance cannot be explained by the genetic segregation of a single gene. Such traits show ...
s. In 2017, he received the
Frank Fenner Prize for Life Scientist of the Year from the
Prime Minister of Australia
The prime minister of Australia is the head of government of the Commonwealth of Australia. The prime minister heads the executive branch of the Australian Government, federal government of Australia and is also accountable to Parliament of A ...
for his work on the basis of genetic variation in complex human traits, such as
obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's we ...
and
schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdra ...
. He has researched the contribution of numerous
single nucleotide polymorphism
In genetics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently larg ...
s to variation in quantitative traits, such as
human height
Human height or stature is the distance from the bottom of the feet to the top of the head in a human body, standing erect. It is measured using a stadiometer, in centimetres when using the metric system or SI system, or feet and inches when ...
, as well as the role of
natural selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charle ...
in driving genetic variation in such traits. He and his colleagues have also used genetic data on common diseases to study potential environmental risk factors for them.
References
External links
Faculty page
*
1981 births
Living people
Chinese geneticists
Chinese statisticians
Statistical geneticists
Chinese expatriates in Australia
Academic staff of the University of Queensland
Zhejiang University alumni
Scientists from Wenzhou
21st-century Chinese scientists
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