Jerry Adams (basketball)
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Jerry McKee Adams, FAA, FRS, FAHMS, FRSV (born 17 June 1940) is an Australian-American
molecular biologist Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
whose research into the genetics of haemopoietic differentiation and malignancy, led him and his wife, Professor Suzanne Cory, to be the first two scientists to pioneer gene cloning techniques in
Australia Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
, and to successfully clone
mammal Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...
ian genes. Adams currently shares (with Andreas Strasser) the position of Joint-Head of the Molecular Genetics of Cancer Division at
The Walter and Eliza Hall Institute of Medical Research WEHI (), previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for ...
(WEHI) in Melbourne (
Australia Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
). Their research, following that by
Susumu Tonegawa is a Japanese scientist who was the sole recipient of the Nobel Prize for Physiology or Medicine in 1987 for his discovery of V(D)J recombination, the Genetics, genetic mechanism which produces antibody diversity. Although he won the Nobel Prize ...
, also led to the discovery that antibody genes encode as bits and pieces, that can recombine in a myriad of ways to help fight infection; they also confirmed earlier work by Shen-Ong & Cole, Leder, Hood, Croce, and Hayward that genetic mutation leads to
Burkitt's lymphoma Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. ...
, a malignancy of antibody-producing cells, called " B lymphocytes". It was in Adams' lab that his PhD student, David Vaux, made the connection between
apoptosis Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes incl ...
(programmed cell death) and cancer, while studying the bcl-2 gene in
follicular lymphoma Follicular lymphoma (FL) is a cancer that involves certain types of white blood cells known as lymphocytes. The cancer originates from the uncontrolled division of specific types of B-cells known as centrocytes and centroblasts. These cells normal ...
, the most common human lymphoma.


Career

He studied for his B.Sc at Emory University in Atlanta, Georgia. After completing his PhD at the Harvard University, Adams was awarded the Helen Hay Whitney Fellowship to pursue post-doctoral training. He spent a year working under Professor
James Watson James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and ...
at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England, during which he met Suzanne Cory, and started their long-term collaboration. They moved to the ''Institut de Biologie Moléculaire'', at the University of Geneva, where they worked under Professor A. Tissiéres. Adams and Cory subsequently moved to
Australia Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
, and began working at
WEHI WEHI (), previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for ...
where they established the Institute's first molecular genetics laboratory. Their research first looked into how
lymphocytes A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic adap ...
could produce so many different
antibodies An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...
, providing insights into the constant and variable segments of antibodies, and how they are rearranged and deleted. Next, Adams and his team moved into the study of the genetics of cancer. In 2007, Adams was appointed member of the Medical Research Advisory Committee at the
Australian Cancer Research Foundation The Australian Cancer Research Foundation (ACRF) is an Australian not-for-profit organisation which funds research into the prevention, diagnosis and treatment of all types of cancer. It provides multimillion-dollar grants for high-end research equ ...
(ACRF). He is part of a group of leading scientists who assess applications for grants for medical research received by the ACRF.


Honours and recognition

Adams was awarded the Lemberg Medal in 1986. He was elected a Fellow of the Royal Society in 1992 and of the Royal Society of Victoria (FRSV) in 1997. In 2014 he was awarded the
Macfarlane Burnet Medal and Lecture The Macfarlane Burnet Medal and Lecture is a biennial award given by the Australian Academy of Science to recognise outstanding scientific research in the biological sciences. It was established in 1971 and honours the memory of the Nobel laurea ...
by the Australian Academy of Science. He was elected a Fellow of the
Australian Academy of Health and Medical Sciences The Australian Academy of Health and Medical Sciences is an academy to promote health and medical sciences in Australia. It was established in June 2014. It cites "The Academy will serve the three purposes identified as of high priority in the 20 ...
in 2021.


Private life

He is married to his fellow scientist and collaborator Suzanne Cory; they have 2 children.


References


External links


Adams JM
Author Profile Page on Pubget
MRAC
Biography courtesy of Australian Cancer Research Foundation


Bibliography

* {{DEFAULTSORT:Adams, Jerry 1940 births Living people 21st-century American biologists Australian molecular biologists Place of birth missing (living people) Australian Fellows of the Royal Society Fellows of the Australian Academy of Science WEHI alumni Fellows of the AACR Academy Australian emigrants to the United States Australian expatriates in England Fellows of the Australian Academy of Health and Medical Sciences Emory University alumni Harvard University alumni