Jeffrey Victor Ravetch (born 1951) is a professor and head of the Laboratory of Molecular Genetics and Immunology at

The Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...

Background and training

Ravetch earned his B.S. degree at

Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...

in 1973 in molecular biophysics and biochemistry working with Donald Crothers on the thermodynamic and kinetic properties of synthetic oligoribonucleotides. He received a Ph.D. from The Rockefeller University in 1978 in bacterial genetics working in the laboratory of

Norton Zinder Norton David Zinder (November 7, 1928 – February 3, 2012) was an American biologist famous for his discovery of genetic transduction. Zinder was born in New York City, received his A.B. from Columbia University in 1947, Ph.D. from the Univers ...

and Peter Model in the Laboratory of Genetics at Rockefeller and an M.D. from

Cornell University Medical School The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York (state), New York. Weill Cornell Medicine is af ...

in 1979. He completed postdoctoral studies at the National Institutes of Health with

Philip Leder Philip Leder (November 19, 1934 – February 2, 2020) was an American geneticist. Early life and education Leder was born in Washington, D.C. and studied at Harvard University, graduating in 1956. In 1960, he graduated from Harvard Medical Sc ...

, where he identified and characterized the genes for human antibodies and the DNA elements involved in switch recombination. From 1982 to 1996 Dr. Ravetch was a member of the faculty of

Memorial Sloan-Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute– ...

and Cornell Medical College. Currently, Ravetch is the Theresa and Eugene M. Lang Professor in the Leonard Wagner Laboratory of Molecular Genetics and Immunology at The Rockefeller University.

Summary of research achievements

Ravetch revealed the mechanisms by which antibodies mediate and regulate their diverse in vivo effector functions through the characterization of the structural and functional diversity of the Fc region and their interactions with the family of Fc receptors he defined. His studies have focused on the redesign of antibodies to enhance their therapeutic capacity for the treatment of infectious, neoplastic and inflammatory diseases.

Selected honors and awards

* Member, National Academy of Sciences, 2006 * Recipient, William B. Coley Award, Cancer Research Institute, 2007 * Member, Institute of Medicine, 2007 * Recipient, Gairdner International Award, 2012 * Recipient, Sanofi-Institut Pasteur Award, 2012, * Recipient, Honorary Doctorate, Friedrich-Alexander-University Erlangen-Nürnberg, 2013 * Recipient,

Wolf Prize in Medicine The Wolf Prize in Medicine is awarded annually by the Wolf Foundation in Israel. It is one of the six Wolf Prizes established by the Foundation and awarded since 1978; the others are in Agriculture, Chemistry, Mathematics, Physics and Arts. The ...

, 2015 * Recipient, Ross Prize in Molecular Medicine, 2017 * Recipient, Robert Koch Medal and Award, 2018

References

{{DEFAULTSORT:Ravetch, Jeffrey V. 1951 births Living people American immunologists Rockefeller University faculty Yale University alumni Rockefeller University alumni Weill Cornell Medical College alumni Members of the National Academy of Medicine