Jean-Pierre Morat (18 April 1846 – 25 July 1920) was a French

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...

born in Saint-Sorlin, department

Saône-et-Loire Saône-et-Loire (; Arpitan: ''Sona-et-Lêre'') is a department in the Bourgogne-Franche-Comté region in France. It is named after the rivers Saône and Loire, between which it lies, in the country's central-eastern part. Saône-et-Loire is Bo ...

. He studied medicine at École de médecine de

Lyon Lyon,, ; Occitan: ''Lion'', hist. ''Lionés'' also spelled in English as Lyons, is the third-largest city and second-largest metropolitan area of France. It is located at the confluence of the rivers Rhône and Saône, to the northwest of t ...

, traveling to

Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...

in 1873, where he presented his dissertation-thesis on

bone marrow Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic ce ...

, "''Contributions à l’étude de la moelle osseuse''". He remained in Paris for three years, working in the laboratory of

Claude Bernard Claude Bernard (; 12 July 1813 – 10 February 1878) was a French physiologist. Historian I. Bernard Cohen of Harvard University called Bernard "one of the greatest of all men of science". He originated the term ''milieu intérieur'', and the a ...

(1813–1878), of whom, Morat became a devoted disciple. In Paris, he worked closely with

veterinarian A veterinarian (vet), also known as a veterinary surgeon or veterinary physician, is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, vet ...

Henri Toussaint (1847–1890) and physiologist Albert Dastre (1844–1917). With Toussaint, he collaborated on "''Les variations de l’état électrique des muscles''" (Variations of the electrical state of

muscles Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscle ...

), and with Dastre, he undertook extensive research of the

sympathetic nervous system The sympathetic nervous system (SNS) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system. The enteric nervous system is sometimes considered part of th ...

. With Dastre, the "Dastre-Morat Law" is derived, a dictum which states that "the

vasoconstriction Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation, the widening of blood vessel ...

of the

capillaries A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: ...

of the body surface is usually accompanied by

vasodilation Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...

of the internal vessels, especially of the viscera, and vice-versa". Following his years spent in Paris, he became an instructor of physiology at the faculty of medicine in Lille. In 1882 he was appointed professor of physiology at the faculty of medicine in Lyon, a position he maintained until his retirement in 1916. In 1883 he was admitted to the

Société de biologie The Société de biologie is a learned society founded in Paris in 1848. The society was conceived during the French Revolution of 1848. The members of the society held regular meetings and published the proceedings in a new scientific journal. The ...

, and in 1904 was elected as a correspondent to the

Académie de Médecine An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy ...

. In 1916 he became a correspondent of the

Académie des sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at the ...

. Morat had a keen interest in the field of

surgery Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...

, being credited for introducing a process of administering

morphine Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (''Papaver somniferum''). It is mainly used as a analgesic, pain medication, and is also commonly used recreational drug, recreationally, or to make ...

and

atropine Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given i ...

to a patient prior to the administration of

anesthesia Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), ...

. Among his better known writings was the six volume "''Traité de physiologie''" (1904), a work that was co-written with a former student of his, Maurice Doyon (1869–1934).

References

* ''This article is based on a translation of the equivalent article from the

French Wikipedia The French Wikipedia (french: Wikipédia en français) is the French-language edition of Wikipedia, the free online encyclopedia. This edition was started on 23 March 2001, two months after the official creation of Wikipedia. It has article ...

.'' {{DEFAULTSORT:Morat, Jean-Pierre French physiologists 1846 births 1920 deaths People from Saône-et-Loire Academic staff of the University of Lyon Members of the French Academy of Sciences