Jane Hinton
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Jane Hinton (1919–2003) was a pioneer in the study of bacterial antibiotic resistance and one of the first two African-American women to gain the degree of Doctor of Veterinary Medicine (1949). Prior to her veterinary medicine studies at the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universitie ...
, she had been a laboratory technician at Harvard, co-developing the Mueller–Hinton agar, a culture medium that is now commonly used to test bacterial susceptibility to antibiotics. She later practiced as a small animal veterinarian in Massachusetts, and then as a federal government inspector. Hinton was the daughter of William Augustus Hinton, a microbiologist and the first African-American professor at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
.


Early life and education

Jane Hinton was born on May 1, 1919. Her father, William Augustus Hinton (1883–1959), was a
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically pathogenic ones. Bacteriologists are interested in studying and learning about bacteria, ...
and
pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
who was an expert in the diagnosis and treatment of syphilis, including the development of tests for syphilis. The son of former slaves, he was the first African-American professor at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
and the first African-American author of a textbook. He entered laboratory medicine because
racism Racism is the belief that groups of humans possess different behavioral traits corresponding to inherited attributes and can be divided based on the superiority of one race over another. It may also mean prejudice, discrimination, or antagonis ...
in Boston prevented him from gaining an internship in medicine. Jane Hinton's mother was Ada Hawes (b. 1878), a high school teacher and social worker, born in Georgia. William and Ada married in 1909, and had two daughters, Jane and Ann Hinton Jones. Jane Hinton earned her undergraduate degree at the age of 20 from
Simmons College Institutions of learning called Simmons College or Simmons University include: * Simmons University, a women's liberal arts college in Boston, Massachusetts * Simmons College of Kentucky, a historically black college in Louisville, Kentucky * Ha ...
in 1939.


Career

In 1931, Hinton's father developed a Medical Laboratory Techniques course, which was open to women, although that profession was then generally not open to women. Jane Hinton worked in Harvard's laboratories at the time she co-developed the Mueller–Hinton agar with
John Howard Mueller John Howard Mueller (June 13, 1891, Sheffield, Massachusetts – February 14, 1954) was an American biochemist, pathologist, and bacteriologist. He is known as the discoverer of the amino acid methionine in 1921, and as the co-developer, with Jane ...
. This agar was a medium developed to isolate the
Neisseria ''Neisseria'' is a large genus of bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens, '' N. meningitidis'' and ''N. gonorrhoeae''. ''Neisseria'' species are Gram-negativ ...
bacteria that caused
gonorrhea Gonorrhea, colloquially known as the clap, is a sexually transmitted infection (STI) caused by the bacterium ''Neisseria gonorrhoeae''. Infection may involve the genitals, mouth, or rectum. Infected men may experience pain or burning with u ...
and meningogoccal meningitis. Mueller and Hinton discovered that starch within the agar helped aid bacterial growth and prevented bacteria toxins from interfering with antibiotic testing. It became the most widely used
culture medium A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the process of cell proliferation or small plants like the moss ''Physcomitrella patens''. Differe ...
for Neisseria. In the 1960s, tests indicated its suitability for detecting whether bacteria are susceptible to antibiotics. The
Clinical and Laboratory Standards Institute The Clinical and Laboratory Standards Institute (CLSI) is a volunteer-driven, membership-supported, not-for-profit, standards development organization. CLSI promotes the development and use of voluntary laboratory consensus standards and guideline ...
, which establishes the best international laboratory standards, adopted the Kirby–Bauer technique using Mueller–Hinton agar as the
gold standard A gold standard is a monetary system in which the standard economic unit of account is based on a fixed quantity of gold. The gold standard was the basis for the international monetary system from the 1870s to the early 1920s, and from the l ...
for antibiotic testing. During World War II, Hinton also worked as a lab technician in Arizona. After the War, Hinton studied veterinary medicine at the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universitie ...
, gaining her Doctor of Veterinary Medicine (VMD) degree in 1949. She and
Alfreda Johnson Webb Alfreda Johnson Webb (born February 21, 1923 in Mobile, Alabama) was a professor of biology and a doctor of veterinary medicine. She was the first Black woman licensed to practice veterinary medicine in the United States. Early life and educatio ...
, who graduated with a VMD from the Tuskegee Institute (now
Tuskegee University Tuskegee University (Tuskegee or TU), formerly known as the Tuskegee Institute, is a private, historically black land-grant university in Tuskegee, Alabama. It was founded on Independence Day in 1881 by the state legislature. The campus was de ...
) that year, were the first African-American women veterinarians. There had been only four African-American VMD graduates at the University of Pennsylvania before Hinton gained her degree, and there would not be another until 1968. Hinton and Webb were also the first African-American members of the Women's Veterinary Medicine Association. After gaining her degree, Hinton practiced as a small animal veterinarian in Canton, Massachusetts, and then a federal government inspector in
Framingham, Massachusetts Framingham () is a city in the Commonwealth of Massachusetts in the United States. Incorporated in 1700, it is located in Middlesex County and the MetroWest subregion of the Greater Boston metropolitan area. The city proper covers with a pop ...
. Jane Hinton, together with John Taylor, the first African-American graduate of the University of Pennsylvania veterinary medicine school, were honored during the school's centennial celebrations by the Minority Veterinary Students association in 1984. Jane Hinton died on April 9, 2003.


References

{{DEFAULTSORT:Hinton, Jane 1919 births 2003 deaths African-American scientists African-American women academics American women academics African-American academics University of Pennsylvania School of Veterinary Medicine alumni American veterinarians 20th-century African-American women 20th-century African-American people 20th-century American people 21st-century African-American people 21st-century African-American women Harvard University staff