Group photo of London Medical students who went to Belsen Wellcome L0029073

Sir James Learmonth Gowans (7 May 1924 – 1 April 2020) was a British

physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...

and immunologist. In 1945, while studying medicine at

King's College Hospital King's College Hospital is a major teaching hospital and major trauma centre in Denmark Hill, Camberwell in the London Borough of Lambeth, referred to locally and by staff simply as "King's" or abbreviated internally to "KCH". It is managed b ...

, he assisted at the liberated

Bergen-Belsen concentration camp Bergen-Belsen , or Belsen, was a Nazi concentration camp in what is today Lower Saxony in northern Germany, southwest of the town of Bergen near Celle. Originally established as a prisoner of war camp, in 1943, parts of it became a concentra ...

as a voluntary medical student. Gowans was born in

Sheffield Sheffield is a city in South Yorkshire, England, whose name derives from the River Sheaf which runs through it. The city serves as the administrative centre of the City of Sheffield. It is historically part of the West Riding of Yorkshire a ...

, England. He graduated in medicine in 1947 from King's College Hospital, then in 1948 obtained a degree in

physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...

at Oxford, followed by a Ph.D. with Howard Florey at the

Sir William Dunn School of Pathology The Sir William Dunn School of Pathology is a department within the University of Oxford. Its research programme includes the cellular and molecular biology of pathogens, the immune response, cancer and cardiovascular disease. It teaches undergra ...

at Oxford on

lymphocyte A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic ad ...

s. He then became a professor of experimental pathology at Oxford. In 1977, he left his research career for ten years to be secretary of the Medical Research Council. He served as Secretary-General of the

Human Frontier Science Program } The International Human Frontier Science Program Organization (HFSPO) is a non-profit organization, based in Strasbourg, France, that funds basic research in life sciences. The organization implements the Human Frontier Science Program (HFSP) and ...

in 1989. He was a colleague and life-long friend of

George Bellamy Mackaness George Bellamy Mackaness (20 August 1922 – 4 March 2007) was an Australian professor of microbiology, immunology, immunologist, writer and administrator, who researched and described the life history of the macrophage. He showed that by infect ...

. He made significant discoveries about the role of lymphocytes in the

immune response An immune response is a reaction which occurs within an organism for the purpose of defending against foreign invaders. These invaders include a wide variety of different microorganisms including viruses, bacteria, parasites, and fungi which could ...

. In particular, he showed that some lymphocytes were not short-lived, as previously assumed, but moved from the blood into the lymphatic system and back. On the initiative of

Peter Medawar Sir Peter Brian Medawar (; 28 February 1915 – 2 October 1987) was a Brazilian-British biologist and writer, whose works on graft rejection and the discovery of acquired immune tolerance have been fundamental to the medical practice of tissu ...

he also undertook experiments on rats that showed that lymphocytes play an important role in

transplant rejection Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient ...

. In 1963, Gowans became a

Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathemat ...

. He was appointed a

Commander of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established ...

in the

1971 New Year Honours The New Year Honours 1971 were appointments in many of the Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. They were announced in supplements to the ''Lond ...

for services to medical science and a

Knight Bachelor The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised orders of chivalry; it is a part of the British honours system. Knights Bachelor are th ...

in the

1982 New Year Honours The New Year Honours 1982 were appointments by most of the Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries, and honorary ones to citizens of other countrie ...

. In 1980, he was awarded the

Wolf Prize in Medicine The Wolf Prize in Medicine is awarded annually by the Wolf Foundation in Israel. It is one of the six Wolf Prizes established by the Foundation and awarded since 1978; the others are in Agriculture, Chemistry, Mathematics, Physics and Arts. The ...

. He was a foreign member of the National Academy of Sciences and a SSI Honorary Member (1971), and received several

honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad hon ...

s. In 1968 he received the

Gairdner Foundation International Award The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a ...

and in 1990 shared the first Medawar Prize with

Jacques Miller Jacques Francis Albert Pierre Miller AC FRS FAA (born 2 April 1931) is a French-Australian research scientist. He is known for having discovered the function of the thymus and for the identification, in mammalian species of the two major subset ...

. In 1974, he was awarded the

Paul Ehrlich and Ludwig Darmstaedter Prize The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for investigations in medicine. It carries a prize money of 120,000 Euro. The prize awarding ceremony is traditionally held on March 14, the birthday of N ...

. He won the Royal Medal in 1976.

Family

In 1956, he married Moira Leatham, with whom he had a son and two daughters.

References

* {{DEFAULTSORT:Gowans, James Learmonth 1924 births 2020 deaths Alumni of King's College London Alumni of Lincoln College, Oxford Knights Bachelor Royal Medal winners 20th-century English medical doctors Fellows of the Royal College of Physicians Fellows of the Royal Society London medical students who assisted at Belsen Foreign associates of the National Academy of Sciences Fellows of King's College London

Family

See also

References