James Bloodworth Jr.
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James Morgan Bartow Bloodworth Jr. (February 21, 1925 – September 22, 2006) was an American
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
,
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
, and researcher on
diabetes mellitus Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...
. He was born in
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
on February 21, 1925, to J. M. Bartow Bloodworth, Sr.—an
attorney Attorney may refer to: * Lawyer ** Attorney at law, in some jurisdictions * Attorney, one who has power of attorney * ''The Attorney'', a 2013 South Korean film See also * Attorney general, the principal legal officer of (or advisor to) a gove ...
—and Elizabeth (née Dimmock) Bloodworth. Bloodworth died on September 22, 2006, in
Madison, Wisconsin Madison is the county seat of Dane County and the capital city of the U.S. state of Wisconsin. As of the 2020 census the population was 269,840, making it the second-largest city in Wisconsin by population, after Milwaukee, and the 80th-lar ...
.


Education

Bloodworth completed his college studies at
Emory University Emory University is a private research university in Atlanta, Georgia. Founded in 1836 as "Emory College" by the Methodist Episcopal Church and named in honor of Methodist bishop John Emory, Emory is the second-oldest private institution of ...
in Atlanta and
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
in
California California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territori ...
, culminating in a B.S. degree from the former school in 1945. Bloodworth also received his
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
from Emory University in 1948. He served a rotating internship at Columbia-Presbyterian Medical Center in
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and went on to pursue residency training at
Ohio State University The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best publ ...
(OSU) in
Columbus, Ohio Columbus () is the state capital and the most populous city in the U.S. state of Ohio. With a 2020 census population of 905,748, it is the 14th-most populous city in the U.S., the second-most populous city in the Midwest, after Chicago, and t ...
.


Professional life

Bloodworth began his academic career as a faculty member at OSU in 1953. In 1962, he accepted a faculty appointment at the
University of Wisconsin Medical School A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, t ...
(UWMS) in Madison. He worked there for the remainder of his career, attaining the rank of full professor. Bloodworth also served as chief of the laboratory service at the
William Shainline Middleton William Shainline Middleton, M.D., M.A.C.P. (7 January 1890 – 9 September 1975) was a prestigious American internist and military physician. He was one of the founders of the American Board of Internal Medicine and its first Secretary-Treasurer ...
Veterans Hospital (MVH) in Madison until 1989. When a new University of Wisconsin Hospital was opened in 1979, Bloodworth became director of the combined
autopsy An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any di ...
service at that institution and the MVH. He had become a national consultant on the use of the autopsy as a quality-control procedure in medicine. As the senior forensic pathologist at the UWMS, he was also a consultant to many Wisconsin county
coroner A coroner is a government or judicial official who is empowered to conduct or order an inquest into Manner of death, the manner or cause of death, and to investigate or confirm the identity of an unknown person who has been found dead within th ...
s. Bloodworth was an active member of several professional societies, including the American Society for Experimental Pathology, the Endocrine Society, the American Diabetes Association, the Society for Experimental Biology and Medicine, and the American Society of Clinical Endocrinology. He served as president of the Wisconsin Society of Pathologists from 1978 to 1980. Bloodworth was a consistently-active medical school instructor in cardiovascular, renal, and endocrine pathology. He also devoted a great deal of his time to the instruction of pathology residents at the UWMS. In order to augment diagnostic accuracy, Bloodworth introduced the use of
electron microscopy An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a hi ...
at that institution. Bloodworth’s personal research interests concerned diabetes mellitus, other endocrine disorders, and renal pathology, and he spoke at many national meetings on those topics. He employed histochemistry and ultrastructural studies to assess lesions of the pancreatic islet cells and blood vessels in patients with diabetes mellitus. In animal models, he was also able to produce changes in the renal glomeruli that recapitulated lesions seen in the kidneys of humans with advanced diabetes. Together with his colleagues, he focused on the causes and prevention of microangiopathy in diabetes mellitus. In particular, his studies of diabetic retinopathy, in collaboration with ophthalmological colleagues at UWMS, defined the progression of changes that eventuate in retinal hemorrhages, plaques, exudates, and other lesions producing visual compromise. His experimental studies in dogs showed that meticulous control of glucose metabolism could effectively prevent
diabetic angiopathy Diabetic angiopathy is a form of angiopathy associated with diabetic complications. While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical. Other forms of diab ...
. For his contributions to the field of endocrinology, Bloodworth received the prestigious Eli Lilly Research Award on behalf of the American Diabetes Association in 1963. Bloodworth’s professional activities also included other areas of endocrine pathology as well. In 1968, he edited and largely authored the first systematic textbook on the pathology of the
endocrine system The endocrine system is a messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. In vertebrates, the hypothalamus is the neu ...
. That publication was subsequently updated by Bloodworth in 1982 and continued in a third edition, edited by Juan Lechago and Victor Gould.''Bloodworth's Endocrine Pathology'', Ed. 3 (Lechago J, Gould VE, Eds), Williams & Wilkins, Baltimore, 1997.


Personal life and death

Bloodworth married Jean Stone in 1947 and had three daughters with her. In 1972, he married Joan Wiltgen and had two more daughters. Bloodworth retired in 1995. He died of cardiovascular disease in September 2006 in Madison, Wisconsin, where he is buried. In addition to his immediate family, Bloodworth was survived by a younger brother, A. W. Franklin Bloodworth, a retired attorney in Atlanta, Georgia.


References

{{DEFAULTSORT:Bloodworth, James, Jr. American pathologists University of Wisconsin–Madison faculty 1925 births 2006 deaths American diabetologists American endocrinologists Emory University alumni Stanford University alumni Ohio State University faculty People from Atlanta Writers from Georgia (U.S. state) Writers from Madison, Wisconsin Emory University School of Medicine alumni 20th-century American male writers