Jamaica Ginger
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Jamaica ginger extract, known in the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
by the slang name Jake, was a late 19th-century
patent medicine A patent medicine (sometimes called a proprietary medicine) is a non-prescription medicine or medicinal preparation that is typically protected and advertised by a trademark and trade name, and claimed to be effective against minor disorders a ...
that provided a convenient way to obtain alcohol during the era of
Prohibition Prohibition is the act or practice of forbidding something by law; more particularly the term refers to the banning of the manufacture, storage (whether in barrels or in bottles), transportation, sale, possession, and consumption of alcoholic b ...
, since it contained approximately 70% to 80%
ethanol Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the ps ...
by weight. In the 1930s, a large number of users of Jamaica ginger were afflicted with a paralysis of the hands and feet that quickly became known as Jamaica ginger paralysis or jake paralysis.


Composition

While Jamaica ginger was essentially an
infusion Infusion is the process of extracting chemical compounds or flavors from plant material in a solvent such as water, oil or alcohol, by allowing the material to remain suspended in the solvent over time (a process often called steeping). An inf ...
of ginger, the US government required solids to be added with the intention of making it less palatable as a way to obtain alcohol legally. The solids expected to be added were particles of ginger root, which made the "medicine" unpalatable. Manufacturers sought solids which impaired the taste less;
tricresyl phosphate Tricresyl phosphate (TCP), is a mixture of three isomeric organophosphate compounds most notably used as a flame retardant. Other uses include as a plasticizer in manufacturing for lacquers and varnishes and vinyl plastics and as an antiwear addit ...
was used, which the producers later found to be a potent neurotoxin; adulterated Jake is estimated to have caused 30,000 to 50,000 people to lose function in their limbs. Trust in Jamaica Ginger was lost, and its production was discontinued.


Early use and Prohibition

Since the 1860s, Jamaica ginger had been widely sold at
drug stores Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medicines. It is a miscellaneous science as it links healt ...
and roadside stands in bottles. In small doses, mixed with water, it was used as a remedy for
headache A headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of Depression (mood), depression in those with severe ...
s, upper respiratory infections,
menstrual disorder A menstrual disorder is characterized as any abnormal condition with regards to a woman's menstrual cycle. There are many different types of menstrual disorders that vary with signs and symptoms, including pain during menstruation, heavy bleeding, ...
s, and
intestinal gas Flatulence is the expulsion of gas from the intestines via the anus, commonly referred to as farting. "Flatus" is the medical word for gas generated in the stomach or bowels. A proportion of intestinal gas may be swallowed environmental air, ...
. Despite its strong
ginger Ginger (''Zingiber officinale'') is a flowering plant whose rhizome, ginger root or ginger, is widely used as a spice and a folk medicine. It is an herbaceous perennial that grows annual pseudostems (false stems made of the rolled bases of l ...
flavour, it was popular as an alcoholic beverage in
dry counties In the United States, a dry county is a county whose local government forbids the sale of any kind of alcoholic beverages. Some prohibit off-premises sale, some prohibit on-premises sale, and some prohibit both. The vast majority of counties no ...
in the United States, where it was a convenient and legal method of obtaining alcohol. It was often mixed with a
soft drink A soft drink (see #Terminology, § Terminology for other names) is a class of non-alcoholic drink, usually (but not necessarily) Carbonated water, carbonated, and typically including added Sweetness, sweetener. Flavors used to be Natural flav ...
to improve the taste. When Prohibition was enacted in 1920, sale of alcohol became illegal nationwide, prompting consumers to search for substitutes. Patent medicines with a high alcohol percentage, such as Jamaica ginger, became obvious choices, as they were legal and available
over the counter Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid pres ...
without prescriptions. By 1921, the United States government made the original formulation of Jamaica ginger prescription-only. Only a fluid extract version defined in the
United States Pharmacopeia The ''United States Pharmacopeia'' (''USP'') is a pharmacopeia (compendium of drug information) for the United States published annually by the over 200-year old United States Pharmacopeial Convention (usually also called the USP), a nonprofi ...
, with a high content of bitter-tasting ginger
oleoresin Oleoresins are semi-solid extracts composed of resin and essential or fatty oil, obtained by evaporation of the solvents used for their production. The oleoresin of conifers is known as crude turpentine or gum turpentine, which consists of oil o ...
, remained available in stores. Because of the taste, it was classified as nonpotable, and was therefore legal to sell despite the alcohol content.
United States Department of Agriculture The United States Department of Agriculture (USDA) is an executive department of the United States federal government that aims to meet the needs of commercial farming and livestock food production, promotes agricultural trade and producti ...
agents audited Jamaica ginger manufacturers by boiling samples and weighing the resulting solids, to make sure their products contained sufficiently high quantities of the bitter-tasting ginger. To make their products more palatable, manufacturers of Jamaica ginger began to illegally replace the ginger oleoresin with cheaper ingredients like
molasses Molasses () is a viscous byproduct, principally obtained from the refining of sugarcane or sugar beet juice into sugar. Molasses varies in the amount of sugar, the method of extraction, and the age of the plant. Sugarcane molasses is usuall ...
,
glycerin Glycerol () is a simple triol compound. It is a colorless, odorless, sweet-tasting, viscous liquid. The glycerol backbone is found in lipids known as glycerides. It is also widely used as a sweetener in the food industry and as a humectant in pha ...
, and
castor oil Castor oil is a vegetable oil pressed from castor beans, the seeds of the plant ''Ricinus communis''. The seeds are 40 to 60 percent oil. It is a colourless or pale yellow liquid with a distinct taste and odor. Its boiling point is and its den ...
, cutting costs and significantly diminishing the unpleasant ginger flavor.


Victims


Organophosphate-induced delayed neuropathy

When the price of castor oil increased in the latter portion of the 1920s, Harry Gross, president of Hub Products Corporation, sought an alternative additive for his Jamaica ginger formula. He discarded
ethylene glycol Ethylene glycol ( IUPAC name: ethane-1,2-diol) is an organic compound (a vicinal diol) with the formula . It is mainly used for two purposes: as a raw material in the manufacture of polyester fibers and for antifreeze formulations. It is an odo ...
and
diethylene glycol Diethylene glycol (DEG) is an organic compound with the formula (HOCH2CH2)2O. It is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste. It is a four carbon Dimer (chemistry), dimer of ethylene glycol. It is miscible in ...
as being too volatile, eventually selecting a mixture containing
triorthocresyl phosphate Tricresyl phosphate (TCP), is a mixture of three isomeric organophosphate compounds most notably used as a flame retardant. Other uses include as a plasticizer in manufacturing for lacquers and varnishes and vinyl plastics and as an antiwear addit ...
(TOCP), a
plasticizer A plasticizer ( UK: plasticiser) is a substance that is added to a material to make it softer and more flexible, to increase its plasticity, to decrease its viscosity, and/or to decrease friction during its handling in manufacture. Plasticizer ...
used in
lacquer Lacquer is a type of hard and usually shiny coating or finish applied to materials such as wood or metal. It is most often made from resin extracted from trees and waxes and has been in use since antiquity. Asian lacquerware, which may be c ...
s and
paint finish Sheen is a measure of the reflected light ( glossiness) from a paint finish. ''Glossy'' and ''flat'' (or ''matte'') are typical extreme levels of glossiness of a finish. Gloss paint is shiny and reflects most light in the specular (mirror-like) d ...
ing. Gross was advised by the manufacturer of the mixture, Celluloid Corporation, that it was non-toxic. TOCP was originally thought to be non-toxic; however, it was later determined to be a
neurotoxin Neurotoxins are toxins that are destructive to nervous tissue, nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insult (medical), insultsSpencer 2000 that can adversely affect function ...
that causes axonal damage to the nerve cells in the
nervous system In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. Th ...
of human beings, especially those located in the
spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...
. The resulting type of paralysis is now referred to as
organophosphate-induced delayed neuropathy Organophosphate-induced delayed neuropathy (OPIDN), also called organophosphate-induced delayed polyneuropathy (OPIDP), is a neuropathy caused by killing of neurons in the central nervous system, especially in the spinal cord, as a result of acute ...
, or OPIDN. In 1930, large numbers of Jake users began to find they were unable to use their hands and feet. Some victims could walk, but they had no control over the muscles which would normally have enabled them to point their toes upward. Therefore, they would raise their feet high with the toes flopping downward, which would touch the pavement first followed by their heels. The toe first, heel second pattern made a distinctive "tap-click, tap-click" sound as they walked. This very peculiar gait became known as the jake walk and the jake dance and those afflicted were said to have jake leg, jake foot, or jake paralysis. Additionally, the calves of the legs would soften and hang down and the muscles between the thumbs and fingers would
atrophy Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations (which can destroy the gene to build up the organ), malnutrition, poor nourishment, poor circulatory system, circulation, loss of hormone, ...
. Within a few months, the TOCP-adulterated Jake was identified as the cause of the paralysis, and the contaminated Jake was recovered. But by that time, it was too late for many victims. Some did recover full, or partial, use of their limbs. But for most, the loss was permanent. The total number of victims was never accurately determined, but is frequently quoted as between 30,000 and 50,000. Many victims were
immigrants Immigration is the international movement of people to a destination country of which they are not usual residents or where they do not possess nationality in order to settle as permanent residents. Commuters, tourists, and other short- ...
to the United States, and most were poor, with little political or social influence. The victims received very little assistance. Harry Gross and his part-owner of Boston-Hub Products, Max Reisman, were ultimately fined $1,000 each and given a two-year suspended jail sentence. Several
blues Blues is a music genre and musical form that originated among African Americans in the Deep South of the United States around the 1860s. Blues has incorporated spiritual (music), spirituals, work songs, field hollers, Ring shout, shouts, cha ...
songs on the subject were recorded in the early 1930s, such as "Jake Walk Papa" by Asa Martin, and "Jake Liquor Blues" by
Ishman Bracey Ishmon Bracey (January 9, 1899 or 1901 – February 12, 1970), sometimes credited as Ishman Bracey, was an American Delta blues singer-guitarist. Alongside his contemporary Tommy Johnson, Bracey was a highly influential bluesman in Jackson, M ...
. Although this incident became well known, later cases of
organophosphate poisoning Organophosphate poisoning is poisoning due to organophosphates (OPs). Organophosphates are used as insecticides, medications, and nerve agents. Symptoms include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, m ...
occurred in Germany, Spain, Italy, and, on a large scale, in
Morocco Morocco, officially the Kingdom of Morocco, is a country in the Maghreb region of North Africa. It has coastlines on the Mediterranean Sea to the north and the Atlantic Ocean to the west, and has land borders with Algeria to Algeria–Morocc ...
in 1959, where cooking oil adulterated with jet engine lubricant from an American airbase led to paralysis in approximately 10,000 victims, and caused an international incident.


Cultural references


Books

* In Sara Gruen's 2006 novel ''
Water for Elephants Water is an inorganic compound with the chemical formula . It is a transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance. It is the main constituent of Earth's hydrosphere and the fluids of all known liv ...
'' jake paralysis afflicts one character, Camel, after drinking contaminated Jamaica Ginger. * In the novel '' The Black Dahlia'', the protagonist reveals early on that his mother went blind and fell to her death after drinking jake, leading to his resentment of his father for purchasing it. * In his autobiography '' On the Move: A Life,''
Oliver Sacks Oliver Wolf Sacks (9 July 1933 – 30 August 2015) was a British neurology, neurologist, Natural history, naturalist, historian of science, and writer. Born in London, Sacks received his medical degree in 1958 from The Queen's College, Oxford ...
describes research that he conducted to develop an animal model of jake paralysis. He was able to duplicate the toxic effects of TOCP on myelinated neurons in earthworms and chickens. * In Jamie Ford's novel '' Hotel on the Corner of Bitter and Sweet'' the two young characters Henry and Keiko are given a prescription for Jamaican Ginger in the 1942 portion of the story. They go to the pharmacy, pick up the bottles, and return to the Black Elks club. Due to war rationing and systemic oppression at the time, the black jazz club is not allowed to have a liquor license, so the proprietor uses Jamaican Ginger to make bathtub gin.


Music

Songs were recorded at the time about "jake" and its effects; in a variety of musical styles, including
blues Blues is a music genre and musical form that originated among African Americans in the Deep South of the United States around the 1860s. Blues has incorporated spiritual (music), spirituals, work songs, field hollers, Ring shout, shouts, cha ...
and
country A country is a distinct part of the world, such as a state, nation, or other political entity. When referring to a specific polity, the term "country" may refer to a sovereign state, state with limited recognition, constituent country, ...
. Several have been included on the compilation albums ''Jake Walk Blues'' (1977, 14 songs) and ''Jake Leg Blues'' (1994, 16 songs) There is a marked but unsurprising duplication of songs between those albums. In some cases, different artists used the same title for different songs. The songs on one or both of those albums are, in alphabetic order by title: * "Alcohol and Jake Blues" Tommy Johnson (1930,
Paramount Paramount (from the word ''paramount'' meaning "above all others") may refer to: Entertainment and music companies * Paramount Global, also known simply as Paramount, an American mass media company formerly known as ViacomCBS. **Paramount Picture ...
12950) * "Bay Rum Blues" - David McCarn and Howard Long * "Bear Cat Papa Blues"
Gene Autry Orvon Grover "Gene" Autry (September 29, 1907 – October 2, 1998), nicknamed the Singing Cowboy, was an American actor, musician, singer, composer, rodeo performer, and baseball team owner, who largely gained fame by singing in a Crooner ...
and Frankie Marvin (1931, unreleased) * "Beer Drinkin' Woman" - Black Ace * "Got the Jake Leg Too" - The Ray Brothers (1930, Victor V-23508) * "Jake Bottle Blues" - Lemuel Turner (1928, Victor V-40052) * "Jake Head Boogie" -
Lightnin' Hopkins Samuel John "Lightnin'" Hopkins (March 15, 1912 – January 30, 1982) was an American country blues singer, songwriter, guitarist and occasional pianist from Centerville, Texas. In 2010, ''Rolling Stone'' magazine ranked him No. 71 on its li ...
(c. 1949-1950) * "Jake Jigga Juke" - Iron Mike Norton (2005, GFO Records) * "Jake Leg Blues" - Willie ("Poor Boy") Lofton (1935,
Decca Decca may refer to: Music * Decca Records or Decca Music Group, record label * Decca Gold, classical music record label owned by Universal Music Group * Decca Broadway, musical theater record label * Decca Studios, recording facility in West ...
7076) * "Jake Leg Blues" -
Mississippi Sheiks The Mississippi Sheiks were a popular and influential American guitar and fiddle group of the 1930s. They were notable mostly for playing country blues but were adept at many styles of popular music of the time. They recorded around 70 tracks ...
with
Bo Carter Armenter (or Armentia) Chatmon (March 21, 1893 or January 1894 – September 21, 1964), known as Bo Carter, was an early American blues musician. He was a member of the Mississippi Sheiks in concerts and on a few of their recordings. He also m ...
(1930,
Okeh OKeh Records () is an American record label founded by the Otto Heinemann Phonograph Corporation, a phonograph supplier established in 1916, which branched out into phonograph records in 1918. The name originally was spelled "OkeH" from the init ...
8939) * "Jake Leg Rag" - W. T. ("Willie") Narmour and S. W. ("Shell" or "Shellie") Smith * "Jake Leg Wobble" - The Ray Brothers (1930, Victor V-40291) * "Jake Legs Blues" - Maynard Britton * "Jake Legs Blues" - Byrd Moore * "Jake Liquor Blues" -
Ishmon Bracey Ishmon Bracey (January 9, 1899 or 1901 – February 12, 1970), sometimes credited as Ishman Bracey, was an American Delta blues singer-guitarist. Alongside his contemporary Tommy Johnson, Bracey was a highly influential bluesman in Jackson, M ...
(1929, Paramount 12941) * "Jake Walk Blues" - The Allen Brothers (1931, Victor V-40303) * "Jake Walk Blues" - Maynard Britton * "Jake Walk Papa" - Asa Martin (1933) * "Limber Neck Rag" - W. T. Narmour and S. W. Smith Other musical references include: *
Savannah, Georgia Savannah ( ) is the oldest city in the U.S. state of Georgia (U.S. state), Georgia and the county seat of Chatham County, Georgia, Chatham County. Established in 1733 on the Savannah River, the city of Savannah became the Kingdom of Great Brita ...
-based band
Baroness Baron is a rank of nobility or title of honour, often hereditary, in various European countries, either current or historical. The female equivalent is baroness. Typically, the title denotes an aristocrat who ranks higher than a lord or knight ...
recorded a song called "Jake Leg" for their album Blue Record.


Film and television

* Jamaica ginger ("Ginger Jake") is a plot element in two episodes of ''
The Untouchables Untouchable or Untouchables may refer to: People * Untouchability, the practice of socially ostracizing a minority group of very low social status * Untouchables, word for the Dalits or Scheduled Castes of India * Untouchables (law enforcement), ...
'', an American TV series.Staff Writer
"The Jamaica Ginger Story"
'' TV.com'', Date Unknown
"The Jamaica Ginger Story" aired in season 2 on February 2, 1961. "Jake Dance" aired on January 22, 1963. * "Ginger Jake" also makes an appearance in the movie ''
Quid Pro Quo ''Quid pro quo'' (Latin: "something for something") is a Latin phrase used in English to mean an exchange of goods or services, in which one transfer is contingent upon the other; "a favor for a favor". Phrases with similar meanings include: " ...
'', where "wannabes" (people who would like to be disabled) are helped by Ginger Jake to become disabled.


References


Further reading

*Baum, Dan, "Jake Leg", ''The New Yorker'' September 15, 2003, p. 50-57
(PDF)
* Blum, Deborah. ''The Poisoner's Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York'' (Penguin Press, February 18, 2010) * Burns, Eric. ''The Spirits of America: A Social History of Alcohol'' (Philadelphia: Temple University Press, 2003) pp. 221–223 * Kidd, J. G, and Langworthy, O. R. Jake paralysis. Paralysis following the ingestion of Jamaica ginger extract adulterated with triortho-cresyl phosphate. ''
Bulletin of the Johns Hopkins Hospital The Johns Hopkins Medical Journal was a medical journal published by the Johns Hopkins University that ceased publication in 1982. It was established in December 1889 as ''The Johns Hopkins Hospital Bulletin''. It was renamed ''Bulletin of the John ...
'', 1933, ''52'', 39. * Gussow, Leon MD. The Jake Walk and Limber Trouble: A Toxicology Epidemic. ''Emergency Medicine News"". ''26(10):48'', October 2004.

' * Morgan, John P. and Tulloss, Thomas C. The Jake Walk Blues: A toxicological tragedy mirrored in popular music. ''JEMF'' (John Edward s Memorial Foundation) ''Quarterly'', 1977, 122-126. * * U.S. Congress, Office of Technology Assessment, Neurotoxicity: Identifying and Controlling Poisons of the Nervous System, OTA-BA-436 (Washington, DC: U.S. Government Printing Office, April 1990). *Kearney, Paul W. ''Our Food and Drug G-Men''
The Progressive ''The Progressive'' is a left-leaning American magazine and website covering politics and culture. Founded in 1909 by U.S. senator Robert M. La Follette Sr. and co-edited with his wife Belle Case La Follette, it was originally called ''La Foll ...
July 10, 1944


External links


The Epidemiologic Side of Toxicology (slides 6 - 10 deal with the Jamaica Ginger Epidemic)The Jake Leg Infamy. This film was originally shown September 2009, at the North American College of Clinical Toxicology meeting in San Antonio, TX. It was part of the Toxicology Historical Society component. It has a Standard YouTube License.
{{DEFAULTSORT:Jamaica Ginger Patent medicines Prohibition in the United States Toxicology Adulteration