Jakob Erdheim
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Jakob Erdheim (24 May 1874,
Boryslav Boryslav ( uk, Борислав; pl, Borysław) is a city located on the Tysmenytsia (river), Tysmenytsia (a tributary of the Dniester), in Drohobych Raion, Lviv Oblast (Oblast, region) of western Ukraine. It hosts the administration of Borysl ...
, Galicia – 18 April 1937,
Vienna en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST ...
) was an Austrian
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
.Österreichisches Biographisches Lexikon 1815-1950
(biography in German)
He is credited with the characterization (or partial characterization) of
Erdheim–Chester disease Erdheim–Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non- Langerhans-cel ...
and
cystic medial necrosis Familial thoracic aortic aneurysm is an autosomal dominant disorder of large arteries. There is an association between familial thoracic aortic aneurysm and Marfan syndrome as well as other hereditary connective tissue disorders. Signs and symp ...
. He was born into a Jewish family in Boryslav. In 1901 he received his medical doctorate from the
University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich histor ...
, later working as an assistant at the institute of
pathological anatomy Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination ...
in Vienna. In 1913 he became habilitated for pathological anatomy, and in 1916 was named director of the pathological-anatomical institute at Vienna city hospital.Jakob Erdheim
@
Who Named It ''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograph ...
From 1924 onward, he was associated with the "Krankenhaus der Stadt Wien-Lainz". He distinguished himself in research of
hyperparathyroidism Hyperparathyroidism is an increase in parathyroid hormone (PTH) levels in the blood. This occurs from a disorder either within the parathyroid glands (primary hyperparathyroidism) or as response to external stimuli (secondary hyperparathyroidism). ...
,
acromegaly Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Other ...
, Paget’s disease and
pituitary gland In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The ...
abnormalities. His name is associated with "Erdheim's syndrome", a condition that is also known as "Scaglietti-Dagnini syndrome" ( cervical spondylosis secondary to acromegaly). Other eponyms associated with him are: * Erdheim disease: a synonym for
cystic medial necrosis Familial thoracic aortic aneurysm is an autosomal dominant disorder of large arteries. There is an association between familial thoracic aortic aneurysm and Marfan syndrome as well as other hereditary connective tissue disorders. Signs and symp ...
. * Erdheim tumor: a synonym for
craniopharyngioma A craniopharyngioma is a rare type of brain tumor derived from pituitary gland embryonic tissue that occurs most commonly in children, but also affects adults. It may present at any age, even in the prenatal and neonatal periods, but peak incidence ...
. He used the term "nanosomia pituitaria" to describe
pituitary dwarfism Growth hormone deficiency (GHD), or human growth hormone deficiency, is a medical condition resulting from not enough growth hormone (GH). Generally the most noticeable symptom is that an individual attains a short height. Newborns may also presen ...
.


Published works

* ''Uber Hypophysenganggeschwülste und Hirncholesteatome'', 1904 - On pituitary swelling and brain
cholesteatoma Cholesteatoma is a destructive and expanding growth consisting of keratinizing squamous epithelium in the middle ear and/or mastoid process. Cholesteatomas are not cancerous as the name may suggest, but can cause significant problems because of the ...
. * ''Rachitis und Epithelkörperchen'', 1914 - Rachitis and the
parathyroid gland Parathyroid glands are small endocrine glands in the neck of humans and other tetrapods. Humans usually have four parathyroid glands, located on the back of the thyroid gland in variable locations. The parathyroid gland produces and secretes pa ...
s. * ''Die lebensvorgange im normalen knorpel und seine wucherung bei akromegalie'', 1931 - Life processes of normal
cartilage Cartilage is a resilient and smooth type of connective tissue. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck an ...
and its growth in acromegalia.WorldCat Identities
(publications)


References


External links

* {{DEFAULTSORT:Erdheim, Jakob 1874 births 1937 deaths Austrian pathologists People from Boryslav People from the Kingdom of Galicia and Lodomeria Jews from Galicia (Eastern Europe) Austro-Hungarian Jews Austrian Jews