Jacques Loeb (; ; April 7, 1859 – February 11, 1924) was a German-born American
physiologist
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...
and
biologist
A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
.
Biography
Jacques Loeb, firstborn son of a Jewish family from the German
Eifel
The Eifel (; lb, Äifel, ) is a low mountain range in western Germany and eastern Belgium. It occupies parts of southwestern North Rhine-Westphalia, northwestern Rhineland-Palatinate and the southern area of the German-speaking Community of ...
region, was educated at the universities of Berlin,
Munich
Munich ( ; german: München ; bar, Minga ) is the capital and most populous city of the States of Germany, German state of Bavaria. With a population of 1,558,395 inhabitants as of 31 July 2020, it is the List of cities in Germany by popu ...
, and
Strasburg (M.D. 1884). He took postgraduate courses at the universities of Strasburg and Berlin, and in 1886 became assistant at the physiological institute of the
University of Würzburg
The Julius Maximilian University of Würzburg (also referred to as the University of Würzburg, in German ''Julius-Maximilians-Universität Würzburg'') is a public research university in Würzburg, Germany. The University of Würzburg is one of ...
, remaining there till 1888. In a similar capacity, he then went to Strasburg University. During his vacations he pursued biological researches, at
Kiel
Kiel () is the capital and most populous city in the northern Germany, German state of Schleswig-Holstein, with a population of 246,243 (2021).
Kiel lies approximately north of Hamburg. Due to its geographic location in the southeast of the J ...
in 1888, and at
Naples
Naples (; it, Napoli ; nap, Napule ), from grc, Νεάπολις, Neápolis, lit=new city. is the regional capital of Campania and the third-largest city of Italy, after Rome and Milan, with a population of 909,048 within the city's adminis ...
in 1889 and 1890.
Jacques Loeb first arrived in the United States in 1891 when he accepted a position at
Bryn Mawr College
Bryn Mawr College ( ; Welsh: ) is a women's liberal arts college in Bryn Mawr, Pennsylvania. Founded as a Quaker institution in 1885, Bryn Mawr is one of the Seven Sister colleges, a group of elite, historically women's colleges in the United St ...
, however, they provided insufficient facilities for his work which would later influence his resignation. In 1892, he was called to the
University of Chicago
The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
as assistant professor of physiology and experimental biology, while later becoming associate professor in 1895, and professor of physiology in 1899.
John B. Watson
John Broadus Watson (January 9, 1878 – September 25, 1958) was an American psychologist who popularized the scientific theory of behaviorism, establishing it as a psychological school.Cohn, Aaron S. 2014.Watson, John B." Pp. 1429–1430 in ''T ...
(the "father of Behaviorism") attended Loeb's neurology classes at the University of Chicago. He was elected as a member to the American Philosophical Society in 1899. In 1902, he was called to fill a similar chair at the
University of California
The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Francisco, ...
. Writer
John Fleming Wilson (1877-1922) called
Carmel Point
Carmel Point also known as the Point, is an unincorporated community in Monterey County, California, United States. It is a cape located at the southern city limits of Carmel-by-the-Sea and offers views of Carmel Bay, the mouth of Carmel River, ...
"Point Loeb" after Professor Loeb, one of the many professors who had summer homes on Professors' Row on the edge of
Carmel-by-the-Sea, California.
In 1910, Loeb moved to the Rockefeller Institute for Medical Research in New York, where he headed a department created for him. He remained at Rockefeller (now
Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
) until his death. Throughout his career, Loeb spent some summers at the
Marine Biological Laboratory
The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent ...
in
Woods Hole, Massachusetts
Woods Hole is a census-designated place in the town of Falmouth in Barnstable County, Massachusetts, United States. It lies at the extreme southwest corner of Cape Cod, near Martha's Vineyard and the Elizabeth Islands. The population was 781 ...
, performing experiments on various marine invertebrates. While there, Jacques Loeb performed his most famous experiment, on artificial
parthenogenesis
Parthenogenesis (; from the Greek grc, παρθένος, translit=parthénos, lit=virgin, label=none + grc, γένεσις, translit=génesis, lit=creation, label=none) is a natural form of asexual reproduction in which growth and development ...
. With this experiment, Loeb was able to cause the
sea urchins
Sea urchins () are spiny, globular echinoderms in the class Echinoidea. About 950 species of sea urchin live on the seabed of every ocean and inhabit every depth zone from the intertidal seashore down to . The spherical, hard shells (tests) of ...
' eggs to begin embryonic development without sperm. The slight chemical modifications of the water in which the eggs were kept, served as the stimulus for the development to begin.
Later in 1918, Loeb established and became the first Editor of the ''
Journal of General Physiology
''Journal of General Physiology'' is a Peer review, peer-reviewed scientific journal published by Rockefeller University Press. The journal covers biology, biological, chemical substance, chemical, or Physics, physical mechanisms of broad physiolog ...
.''
Jacques Loeb became one of the most famous scientists in America, widely covered in newspapers and magazines, influencing other important individuals in the scientific world such as
B.F. Skinner
Burrhus Frederic Skinner (March 20, 1904 – August 18, 1990) was an American psychologist, behaviorist, author, inventor, and social philosopher. He was a professor of psychology at Harvard University from 1958 until his retirement in 1974.
...
. He was the model for the character of Max Gottlieb in
Sinclair Lewis
Harry Sinclair Lewis (February 7, 1885 – January 10, 1951) was an American writer and playwright. In 1930, he became the first writer from the United States (and the first from the Americas) to receive the Nobel Prize in Literature, which was ...
's
Pulitzer Pulitzer may refer to:
*Joseph Pulitzer, a 20th century media magnate
*Pulitzer Prize, an annual U.S. journalism, literary, and music award
*Pulitzer (surname)
* Pulitzer, Inc., a U.S. newspaper chain
*Pulitzer Center on Crisis Reporting, a non-pro ...
-winning novel ''
Arrowsmith'', the first great work of fiction to idealize and idolize pure science.
Mark Twain
Samuel Langhorne Clemens (November 30, 1835 – April 21, 1910), known by his pen name Mark Twain, was an American writer, humorist, entrepreneur, publisher, and lecturer. He was praised as the "greatest humorist the United States has p ...
also wrote an essay titled "Dr. Loeb's Incredible Discovery", urging the reader not to support a rigid general consensus, but to instead be open to new scientific advances.
Loeb was nominated many times for the
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...
but never won.
Loeb was an atheist.
[Stout, Harry S., and D. G. Hart. New Directions in American Religious History. New York: Oxford UP, 1997. Print. Loeb was a forthright atheist..."]
Research area
The main subjects of Loeb's work were:
* Animal
tropism
A tropism is a biological phenomenon, indicating growth or turning movement of a biological organism, usually a plant, in response to an environmental stimulus. In tropisms, this response is dependent on the direction of the stimulus (as oppose ...
s and their relation to the instincts of animals
*
Heteromorphosis
Heteromorphosis (//) ( el, έτερος – other; morphe – form) refers to situations where an organ or tissue is different from the expected,"Biology Encyclopedic Dictionary. "Ch. Ed. MS Gilyarov; Editorial Board: AA Babayev, GG Winberg, GA Zav ...
, the replacement of an injured or removed organ by a different organ
* Toxic and antitoxic effects of ions
* Artificial parthenogenesis
* Hybridization of the eggs of sea-urchins by the sperm of starfish
Works
Among Loeb's works the following may be mentioned:
* ''Der Heliotropismus der Thiere und seine Uebereinstimmung mit dem Heliotropismus der Pflanzen'', Würzburg: Verlag von Georg Hertz, 1890.
* ''Untersuchungen zur physiologischen Morphologie der Thiere'', Würzburg: Verlag von Georg Hertz, 1891–1892. 2 vols., vol. 1: ''Ueber Heteromorphose'', vol. 2: ''Organbildung und Wachsthum''.
* ''Einleitung in die vergleichende Gehirnphysiologie und vergleichende Psychologie'', Leipzig: J. A. Barth, 1899. English ed., ''Comparative physiology of the brain and comparative psychology'', New York: Putnam, 1900.
* ''Studies in general physiology'', Chicago: The University of Chicago Press, 1905.
* ''The dynamics of living matter'', New York: Columbia University Press, 1906.
* ''The mechanistic conception of life: biological essays'', Chicago: The University of Chicago Press, 1912; reprint, Cambridge, Mass.: Harvard University Press, 1964.
* ''Artificial parthenogenesis and fertilization'', tr. from German by W. O. Redman King, rev. and ed. by Loeb. Chicago: The University of Chicago Press, 1913.
* ''The organism as a whole, from a physicochemical viewpoint'', New York: Putnam, 1916.
* ''Forced movements, tropisms, and animal conduct'', Philadelphia:
Lippincott, 1918.
* ''Proteins and the theory of colloidal behavior'', New York: McGraw-Hill, 1922.
''The Mechanistic Conception of Life'' is Loeb's most famous and influential work. It contains English translations of some of his previous publications in German.
Family
His younger brother
Leo also emigrated to the United States where he became a noted pathologist.
References
Sources
*
External links
Jacques Loebat The Embryo Project Encyclopedia.
Jacques Loebat the Jewish Encyclopedia.
at infoplease.com.
National Academy of Sciences Biographical Memoir
{{DEFAULTSORT:Loeb, Jacques
1859 births
1924 deaths
Jewish biologists
People from Mayen
People from the Rhine Province
19th-century German Jews
German emigrants to the United States
German physiologists
American atheists
American physiologists
University of Chicago faculty
Rockefeller University people
Members of the United States National Academy of Sciences