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Jacques Dubois ( Latinised as Jacobus Sylvius; 1478 – 14 January 1555) was a French
anatomist Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...
. Dubois was the first to describe venous valves, although their function was later discovered by
William Harvey William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions in anatomy and physiology. He was the first known physician to describe completely, and in detail, the systemic circulation and proper ...
. He was the brother of Franciscus Sylvius Ambianus (François Dubois; c. 1483 – 1536), professor of
humanities Humanities are academic disciplines that study aspects of human society and culture. In the Renaissance, the term contrasted with divinity and referred to what is now called classics, the main area of secular study in universities at the t ...
at the
Collège de Tournai The collège de Tournai was a college of the former University of Paris. It was founded in 1353, along the collège de Boncourt, by the bishop of Tournai, on the montagne Sainte-Geneviève in the (now) 5th arrondissement of Paris. It was later at ...
,
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
.


First years

The origins of this anatomist are vague. He was probably born in 1478 in Loeuilly, See als
''In linguam Gallicam Isagωge''
a small town near
Amiens Amiens (English: or ; ; pcd, Anmien, or ) is a city and commune in northern France, located north of Paris and south-west of Lille. It is the capital of the Somme department in the region of Hauts-de-France. In 2021, the population of ...
, the seventh in a family of fifteen.Kellett, C. E. (1961), "Sylvius and the Reform of Anatomy", ''Med Hist.'' 5(2): 101–116. His father had been a weaver. At a young age he studied
Ancient Greek Ancient Greek includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Dark Ages (), the Archaic peri ...
with
Hermonymus of Sparta George Hermonymus ( el, Γεώργιος Ἑρμώνυμος; born before 1435; died after 1503), also known as Hermonymus of Sparta, was a 15th-century Greek scribe, diplomat, scholar and lecturer. He was the first person to teach Greek at the Col ...
''Revue des bibliothèques'', Volume 15, 1905
p. 268
and
Janus Lascaris Janus Lascaris (, ''Ianos Laskaris''; c. 1445, Constantinople – 7 December 1535, Rome), also called John Rhyndacenus (from Rhyndacus, a country town in Asia Minor), was a noted Greek scholar in the Renaissance. Biography After the Fall of Con ...
, Hebrew with
François Vatable François Vatable (late 15th century – 16 March 1547) was a French humanist scholar, a hellenist and hebraist. Life Born in Gamaches, Picardy, he was for a time rector of Bramet in Valois. In 1530 Francis I of France appointed him as one of ...
, and mathematics with
Jacques Lefèvre d'Étaples Jacques Lefèvre d'Étaples ( Latinized as Jacobus Faber Stapulensis; c. 1455 – c. 1536) was a French theologian and a leading figure in French humanism. He was a precursor of the Protestant movement in France. The "d'Étaples" was not part of ...
, and gradually became a leading figure in
French humanism Humanism in France found its way from Italy, but did not become a distinct movement until the 16th century was well on its way. History On the completion of the Hundred Years' War between France and England, the intellectual currents of Renais ...
, where he was famous for his excellent knowledge of these disciplines.


Early grammar of French

Dubois was the author of the first grammar of the French language to be published in France. The title of this work was ''In linguam gallicam isagωge, una cum eiusdem Grammatica latino-gallica, ex hebræis, græcis et latinis authoribus'' 'Introduction to the French language, with a Latin-French grammar of the same, based on Hebrew, Greek and Latin authors'' published in Paris in early 1531, less than a year after the very first French grammar, by
John Palsgrave John Palsgrave (c. 1485 – 1554) was a priest of Henry VIII of England's court. He is known as a tutor in the royal household, and as a textbook author. Life It is believed that John Palsgrave, who spelled his name in a variety of ways inclu ...
, was published in London.


From philosophy to medicine

Dubois was known for his hard work, and eloquence. He studied languages and mathematics at the
University of Paris , image_name = Coat of arms of the University of Paris.svg , image_size = 150px , caption = Coat of Arms , latin_name = Universitas magistrorum et scholarium Parisiensis , motto = ''Hic et ubique terrarum'' (Latin) , mottoeng = Here and a ...
; but feeling that the rewards were inadequate, Dubois abandoned scholarship for medicine. He acquired his anatomical knowledge thanks to Jean Fagault, a famous physician of Paris and also dean of the Faculty of Medicine. While studying under Fagault, Dubois began his career as a professor with a course explaining the work of
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
and
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
. These lessons concerned anatomy and were taught at the (in
Tréguier Tréguier (; br, Landreger) is a port town in the Côtes-d'Armor department in Brittany in northwestern France. It is the capital of the province of Trégor. Geography Tréguier is located 36 m. N.W. of Saint-Brieuc by road. The port is situat ...
). The success of his lectures turned out to be so remarkable that the faculty of the University of Paris protested that he had not yet obtained a college degree. For this reason Sylvius went to the
University of Montpellier The University of Montpellier (french: Université de Montpellier) is a public university, public research university located in Montpellier, in south-east of France. Established in 1220, the University of Montpellier is one of the oldest univ ...
, where he enrolled in November 1529.A. Wear, R. K. French, I. M. Lonie (eds.), ''The Medical Renaissance of the Sixteenth Century'', Cambridge University Press, 1985, p. 146. He received his M.B. in 1529 and his
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
from Montpellier in 1530. Once he obtained his degree he returned to Paris, but he was again blocked by the Faculty, which decreed that the anatomist should have obtained an M.B. from the University of Paris before returning to his lessons. On 28 June 1531 Sylvius incorporated an M.B. at Paris and was able to resume its course in anatomy. In 1550, when
Vidus Vidius Guido Guidi (Latinized name Vidus Vidius) (10 February 1509 – 26 May 1569), was an Italian surgeon, anatomist and translator. Biography His father was a physician and his mother was the daughter of the painter Domenico Ghirlandajo. After pr ...
departed for Italy, he was appointed to succeed him as Professor of Surgery in charge of the new Collège Royal in Paris. This appointment was granted by Henry II of Valois. Sylvius was an admirer of
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
, and interpreted the anatomical and physiological writings of that author in preference to giving demonstrations from the subject. He died on 14 January 1555 in Paris.


Sylvius as a teacher

Sylvius was not only an eloquent professor, but also a demonstration teacher. He was the first professor to teach anatomy of a human corpse, in France. His biggest intellectual flaw was his blind reverence for the ancient authors. He treated the writings of Galen as if they were wholly sacred, he would believe that if a corpse showed structures different from those described by Galen, the error was not in the texts, but in the corpse, or the structure of the human body that had changed over the centuries. In one of his works, "Ordo et Ratio Ordinis Legendis Hippocratis et Galeni Libris", Sylvius says that the anatomy of Galen was infallible, that his treatise ''De Usu Partium'' was divine and that further progress in anatomy would have been impossible.
Andreas Vesalius Andreas Vesalius (Latinized from Andries van Wezel) () was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, ''De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' '' ...
, who was his (frustrated) pupil, states that his manner of teaching was calculated neither to advance the science nor to rectify the mistakes of his predecessors. A human body was never seen in Dubois' anatomical theatre. The carcasses of dogs and other animals were the materials from which he taught. It was so difficult to obtain human bones, that Vesalius and his fellow-students had to collect them themselves from the
Cimetière des Innocents The Holy Innocents' Cemetery (French: Cimetière des Saints-Innocents or Cimetière des Innocents) is a defunct cemetery in Paris that was used from the Middle Ages until the late 18th century. It was the oldest and largest cemetery in Paris and h ...
and other cemeteries. Without these, they must have committed numerous errors in acquiring the first principles. Though Jean Riolan (1577–1657) contradicted these comments and accused Vesalius of ingratitude, it is certain that the frustrations that Vesalius experienced were the basis for which he later traveled to
Padua Padua ( ; it, Padova ; vec, Pàdova) is a city and ''comune'' in Veneto, northern Italy. Padua is on the river Bacchiglione, west of Venice. It is the capital of the province of Padua. It is also the economic and communications hub of the ...
and became a famous anatomist himself. Only in Italy were the opportunities of inspecting the human body frequent enough as to facilitate the study of the science.
Charles Estienne Charles Estienne (; 1504–1564), known as Carolus Stephanus in Latin and Charles Stephens in English, was an early exponent of the science of anatomy in France. Charles was a younger brother of Robert Estienne I, the famous printer, and son to ...
also attacked his old teacher and assured that Sylvius was greedy. Some other pupils of Sylvius defended his teaching and work, specially Louis Vasse and Michel de Villeneuve, the latter being considered by Johann Winter von Andernach (colleague and friend of Sylvius) the best galenist of Paris and second anatomist after
Vesalius Andreas Vesalius (Latinized from Andries van Wezel) () was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, ''De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' '' ...
. Louis Vassé denounced the attacks of Vesalius and Estienne, and affirmed they had learnt all they knew by Sylvius' lessons. Vasse explains the nature of Sylvius' influence over his unruly audience this way: ''"This depended not so much on his splendid use of the Latin tongue as upon the exceptional clarity of his thought. He was, moreover, never tired of teaching and so taught that none of his students ever tired of learning. He had an astonishing power of enabling them to grasp and see quite clearly that which a moment before had seemed impenetrable and terribly involved."''Vasse, Louis. ''In Anatomen corporis humani Tabulae quatuor''. Paris, 1540. Preface. This period was a time of fierce debate between
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
ists and the new body of thought on anatomy. The conservative Riolan attacked
William Harvey William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions in anatomy and physiology. He was the first known physician to describe completely, and in detail, the systemic circulation and proper ...
with equal fervour.


Contributions to anatomy

Sylvius made a valuable service by giving a name to the muscles, which until then had simply been referred to by numbers. These numbers were arbitrarily assigned by different authors. He was the first anatomist to publish descriptions of satisfactory
pterygoid Pterygoid, from the Greek for 'winglike', may refer to: * Pterygoid bone, a bone of the palate of many vertebrates * Pterygoid processes of the sphenoid bone ** Lateral pterygoid plate ** Medial pterygoid plate * Lateral pterygoid muscle * Medial ...
process and the
sphenoid bone The sphenoid bone is an unpaired bone of the neurocranium. It is situated in the middle of the skull towards the front, in front of the basilar part of occipital bone, basilar part of the occipital bone. The sphenoid bone is one of the seven bones ...
and clinoid bone tear. He gave a good description of the sphenoid sinus in an adult, but denied its existence in children. Sylvius also wrote about the
vertebrae The spinal column, a defining synapomorphy shared by nearly all vertebrates,Hagfish are believed to have secondarily lost their spinal column is a moderately flexible series of vertebrae (singular vertebra), each constituting a characteristic i ...
, but described incorrectly the
sternum The sternum or breastbone is a long flat bone located in the central part of the chest. It connects to the ribs via cartilage and forms the front of the rib cage, thus helping to protect the heart, lungs, and major blood vessels from injury. Sh ...
. Although the
cerebral aqueduct The cerebral aqueduct (aqueductus mesencephali, mesencephalic duct, sylvian aqueduct or aqueduct of Sylvius) is a conduit for cerebrospinal fluid (CSF) that connects the third ventricle to the fourth ventricle of the ventricular system of the brai ...
(Aqueduct of Sylvius) and Sylvian (lateral) sulcus of the brain have been said to be his contributions to anatomy, the aqueduct was described by Galen nearly 1300 years before, albeit the name aqueduct in this context was first mentioned by another Sylvius (
Franciscus Sylvius Franciscus Sylvius (15 March 1614 – 19 November 1672), born Franz de le Boë, was a Dutch physician and scientist (chemist, physiologist and anatomist) who was an early champion of Descartes', Van Helmont's and William Harvey's work and ...
, 1614-1672), who apparently also described the sulcus which bears his name.


References


External links

* {{DEFAULTSORT:Dubois, Jacques 1478 births 1555 deaths French anatomists History of anatomy 16th-century French physicians