JT-010
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JT-010 is a chemical compound which acts as a potent, selective activator of the
TRPA1 Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is a protein that in humans is encoded by the ''TRPA1'' (and in mice and rats by the ''Trpa1' ...
channel, and has been used to study the role of this receptor in the perception of
pain Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
, as well as other actions such as promoting repair of dental tissue after damage.


See also

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ASP-7663 ASP-7663 is a chemical compound which acts as a potent, selective activator of the TRPA1 channel. It has protective effects on cardiac tissue, and is used for research into the function of the TRPA1 receptor. See also * JT-010 JT-010 is a chem ...
*
PF-4840154 PF-4840154 is a pyrimidine derivative discovered by Pfizer at its Sandwich, Kent research center. The compound is a potent, selective activator of both the human (EC50 = 23 nM) and rat (EC50 = 97 nM) TRPA1 channels. This compound elicits nocicept ...


References

{{Transient receptor potential channel modulators Nitrogen mustards Thiazoles Amides Phenyl compounds Ethers Transient receptor potential channel agonists