Isopropyl Myristate
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Isopropyl myristate (IPM) is the
ester In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides ar ...
of
isopropyl alcohol Isopropyl alcohol (IUPAC name propan-2-ol and also called isopropanol or 2-propanol) is a colorless, flammable organic compound with a pungent alcoholic odor. As an isopropyl group linked to a hydroxyl group (chemical formula ) it is the simple ...
and
myristic acid Myristic acid (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH. Its salts and esters are commonly referred to as myristates or tetradecanoates. It is named after the binomial name for nutm ...
.


Uses

Isopropyl myristate is a polar
emollient A moisturizer, or emollient, is a cosmetic preparation used for protecting, moisturizing, and lubricating the skin. These functions are normally performed by sebum produced by healthy skin. The word "emollient" is derived from the Latin verb ''mo ...
and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for
head lice The head louse (''Pediculus humanus capitis'') is an obligate ectoparasite of humans. Head lice are wingless insects that spend their entire lives on the human scalp and feeding exclusively on human blood. Humans are the only known hosts of thi ...
. It is also in flea and tick killing products for pets. It is used to remove bacteria from the oral cavity as the
non-aqueous An aqueous solution is a solution in which the solvent is water. It is mostly shown in chemical equations by appending (aq) to the relevant chemical formula. For example, a solution of table salt, or sodium chloride (NaCl), in water would be r ...
component of the two-phase
mouthwash Mouthwash, mouth rinse, oral rinse, or mouth bath is a liquid which is held in the mouth passively or swilled around the mouth by contraction of the perioral muscles and/or movement of the head, and may be gargling, gargled, where the head is ti ...
product "
Dentyl pH Dentyl Dual Action, previously known as Dentyl Active, and originally as Dentyl pH, is a brand of mouthwash, an oral hygiene product designed to reduce the presence of bacteria responsible for tooth decay, gingivitis and halitosis. Traditional mout ...
". Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of
prosthetic make-up A facial prosthetic or facial prosthesis is an artificial device used to change or adapt the outward appearance of a person's face or head. When used in the theatre, film or television industry, facial prosthetic makeup alters a person's normal f ...
.
Hydrolysis Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution reaction, substitution, elimination reaction, elimination, and solvation reactions in which water ...
of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7


References


External links

* {{Cosmetics Carboxylate esters Cosmetics chemicals Isopropyl esters