Isabelle of Orléans or Isabelle d'Orléans may refer to:
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Élisabeth Marguerite d'Orléans (1646-1696), Duchess of Alençon and Angoulême
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Princess Isabelle of Orléans (1878–1961), member of the French Orleanist royal family and by marriage Duchess of Guise
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Princess Isabelle of Orléans (1900–1983), member of the House of Orléans and by marriage Countess of Harcourt
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Princess Isabelle of Orléans-Braganza (1911–2003), historical author and consort of the Orleanist pretender, Henri, Count of Paris
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