Inositol pentakisphosphate (abbreviated IP5) is a molecule derived from
inositol tetrakisphosphate by adding a
phosphate group
In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphoric acid .
The phosphate or orthophosphate ion is derived from phosph ...
with the help of
Inositol-polyphosphate multikinase (IPMK). It is believed to be one of the many
second messengers in the
inositol phosphate
Inositol phosphates are a group of mono- to hexaphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation.
The group comprises:
* inosito ...
family. It "is implicated in a wide array of biological and pathophysiological responses, including tumorigenesis, invasion and metastasis, therefore specific inhibitors of the kinase may prove useful in cancer therapy."
IP5 also plays a role in defense signaling in plants. It potentiates the interaction of the plant hormone
JA-Ile
Jasmonate (JA) and its derivatives are lipid-based plant hormones that regulate a wide range of processes in plants, ranging from growth and photosynthesis to reproductive development. In particular, JAs are critical for plant defense against herbi ...
by its receptor.
References
Organophosphates
Inositol
Phosphate esters
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