István Tóth is an Australian

scientist A scientist is a person who conducts Scientific method, scientific research to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, ...

and

chemical engineer In the field of engineering, a chemical engineer is a professional, equipped with the knowledge of chemical engineering, who works principally in the chemical industry to convert basic raw materials into a variety of products and deals with the ...

. He is the Chair of Biological Chemistry and Professor of Pharmacy at the

University of Queensland , mottoeng = By means of knowledge and hard work , established = , endowment = A$224.3 million , budget = A$2.1 billion , type = Public research university , chancellor = Peter Varghese , vice_chancellor = Deborah Terry , city = B ...

Education

Has a Master's in Chemical Engineering and a Ph.D. from the Technical University Budapest and is a member of the

Hungarian Academy of Sciences The Hungarian Academy of Sciences ( hu, Magyar Tudományos Akadémia, MTA) is the most important and prestigious learned society of Hungary. Its seat is at the bank of the Danube in Budapest, between Széchenyi rakpart and Akadémia utca. Its ma ...

. Toth is also a fellow of the Queensland Academy of Art and Sciences and

Royal Australian Chemical Institute The Royal Australian Chemical Institute (RACI) is both the qualifying body in Australia for professional chemists and a learned society promoting the science and practice of chemistry in all its branches. The RACI hosts conferences, seminars and ...

, and Affiliated Professorial Research Fellow and Group Leader at Institute of Molecular Biosciences, UQ.

Career

After earning his Ph.D., he spent two years at

Carleton University Carleton University is an English-language public research university in Ottawa, Ontario, Canada. Founded in 1942 as Carleton College, the institution originally operated as a private, non-denominational evening college to serve returning World ...

, Ottawa. In 1977, Toth returned to

Budapest Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population ...

and began working at the Central Research Institute for Chemistry of the Hungarian Academy of Sciences before relocating to the School of Pharmacy University of London in 1987. In 1994, Toth was awarded a DSc degree by the Hungarian Academy of Sciences for his work on drug delivery. He then joined the University of Queensland in 1998 to lead a productive medicinal chemistry research group and became an Australian citizen in the year 2000. Toth is an elected Fellow of the

, Fellow of the Queensland Academy of Arts and Sciences and Member (External) of the

. In 2009, he received the Adrian Albert award for sustained research in medicinal biochemistry. In 2019, he received the Doctor Honoris Causa Degree by the Semmelweis University.

Selected publications

* Zhao, L.; Jin, W.; Cruz, J. G.; Marasini, N.; Khalil, Z, G.; Capon, R. J.; Hussein, W. M.; Skwarczynski, M.; Toth, I. Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 2020, 10, 823; doi:10.3390/nano10050823 * Faruck, M. O.; Zhao, L.; Hussein, W. M.; Khalil, Z. G.; Capon, R. J.; Skwarczynski, M.; Toth I. Polyacrylate-peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus, Vaccines, 2020,8, 23; doi:10.3390/vaccines8010023. * Azuar, A.; Jin, W.; Mukaida, S.; Hussein, W. M.; Toth I.; Skwarczynski, M. Recent Advances in the Development of Peptide Vaccines and their Delivery Systems against Group A Streptococcus Vaccines,2019, 7, 58; doi:10.3390/vaccines7030058. * Khongkowa, M.; Liu, T-Y.; Bartlett, S.; Hussein, W. M.; Nevagi, R.; Jia, Z.; Monteiro, M. J.; Wells, J. W.; Ruktanonchai, U. R.; Skwarczynski, M.; Toth, I. Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Prec. Nanomed. 2018, 1, 186–196. DOI:10.29016/181025.1 * Skwarczynski, M.; Toth, I. Peptide-based synthetic vaccines Chemical Science,2016, 7, 842 – 854.DOI: 10.1039/c5sc03892h * Goodwin, D.; Varamini, P.; Simerska, P.; D'Occhio, M. J.; Toth, I. Design, synthesis and evaluation of a gonadotropin releasing hormone-based subunit vaccine in rams (Ovis aries). Vaccine 2015, 33, 1453–1458. * Stephenson, R.; Varamini, P.; Butcher, N.; Minchin, R.; Toth, I. Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomed.-Nanotechnol. Biol. Med. 2014, 10, 1799–1808. * Deng, Z. J.; Liang, M.; Monteiro, M.; Toth, I.; Minchin, R. F. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nat. Nanotechnol. 2011, 6, 39–44. * Skwarczynski, M.; Zhao, G.; Boer, J. C.; Ozberk, V.; Azuar, A.; Cruz, J. G.; Giddam, A. K.; Khalil, Z. G.; Pandey, M.; Shibu, M. A.; Hussein, W. M.; Nevagi, R.; Batzloff, M. R.; Wells, J. W.; Capon, R. J.; Plebanski, M.; Good, M. F.; Toth, I. Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Sci Adv 2020, 6, eaax2285.

References

External links

* {{DEFAULTSORT:Toth, Istvan Living people Australian chemists Budapest University of Technology and Economics alumni Carleton University alumni 21st-century Australian scientists Academic staff of the University of Queensland Year of birth missing (living people)