Issoufou is a surname and given name. Notable people with the surname include:

Given name

* Issoufou Assoumane, Nigerien politician and ministers of council * Issoufou Boubacar Garba (born 1990), Nigerien footballer * Issoufou Dayo (born 1991), Burkina Faso footballer * Issoufou Habou (born 1945), Nigerien light-middleweight boxer * Issoufou Saidou-Djermakoye (1920– 2000), Nigerien politician * Issoufou Sidibé, Nigerien labour leader and politician * Ousmane Issoufou Oubandawaki (born 1948), Nigerien politician

Surname

* Abdoul Razak Issoufou (born 1994), Nigerien taekwondo practitioner * Alhassane Issoufou (born 1981), Nigerien footballer * Aissata Issoufou Mahamadou, Nigerien chemist, chemical engineer, mining specialist, healthcare advocate and First Lady of Niger * Boubacar Idrissa Issoufou (born 197), Nigerien footballer * Lalla Malika Issoufou (born 1975), Nigerien medical doctor, patron of many charities and First Lady of Niger * Mahamadou Issoufou (born 1952), Nigerien politician, President of Niger Surnames Given names