Isosakuranetin, an
O-methylated flavonoid The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups (methoxy bonds). O-methylation has an effect on the solubility of flavonoids.
Enzymes
O-methylated flavonoids formation implies the presence of spe ...
, is the 4'-methoxy derivative of
naringenin
Naringenin is a flavorless, colorless flavanone, a type of flavonoid. It is the predominant flavanone in grapefruit, and is found in a variety of fruits and herbs.
Structure
Naringenin has the skeleton structure of a flavanone with three hyd ...
, a
flavanone
The flavanones, a type of flavonoids, are various aromatic, colorless ketones derived from flavone that often occur in plants as glycosides.
List of flavanones
* Blumeatin
* Butin
* Eriodictyol
* Hesperetin
* Hesperidin
* Homoeriodictyol
* Iso ...
. Didymin, a disaccharide of isosakuranetin, occur e.g. in sweet orange, blood orange and mandarin. Isosakuranetin is a potent inhibitor of
TRPM3
Transient receptor potential cation channel subfamily M member 3 is a protein that in humans is encoded by the ''TRPM3'' gene.
Function
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels ...
channels.
Glycosides
*
Poncirin
Poncirin is the 7-O-neohesperidoside of isosakuranetin. Poncirin can be extracted from trifoliate orange
The trifoliate orange, ''Citrus trifoliata'' or ''Poncirus trifoliata'', is a member of the family Rutaceae. Whether the trifoliate oranges ...
is the 7-O-
neohesperidoside
Neohesperidose is the disaccharide which is present in some flavonoids. It can be found in species of ''Typha.'' ''Delphinidin-3-neohesperidoside and cyanidin-3- neohesperidoside from receptacles of Podocarpus species, Oyvind M. Andersen, Phytoche ...
of isosakuranetin.
*
Didymin is the 7-O-
rutinoside
Rutinose is the disaccharide also known as 6-''O''-α-L- rhamnosyl-D-glucose (C12H22O10) that is present in some flavonoid glycosides. It is prepared from rutin by hydrolysis
Hydrolysis (; ) is any chemical reaction in which a molecule of wa ...
of isosakuranetin
References
O-methylated flavanones
Flavonoids found in Rutaceae
Resorcinols
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