Isopropylparaben is a

paraben Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. Chemically, they are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Parabens are effective p ...

Synthesis

Isopropylparaben has been prepared via the stepwise addition of

isopropanol Isopropyl alcohol (IUPAC name propan-2-ol and also called isopropanol or 2-propanol) is a colorless, flammable organic compound with a pungent alcoholic odor. As an isopropyl group linked to a hydroxyl group (chemical formula ) it is the simple ...

thionyl chloride Thionyl chloride is an inorganic compound with the chemical formula . It is a moderately volatile, colourless liquid with an unpleasant acrid odour. Thionyl chloride is primarily used as a chlorinating reagent, with approximately per year bein ...

, and ''p''-hydroxybenzoic acid at low temperature, followed by heating the reaction mixture. Sunbin Lu, Qiao Zhou and Shitao Zhou, “A process for preparing isopropyl p-hydroxybenzoate”, Chinese Patent 103,420,841 A 20131204 (2013)

References

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External links

Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products
Cleaning product components Parabens Isopropyl esters