Iraj Lalezari
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Iraj Lalezari (1930–2019) was an Iranian academic of Jewish origin. His study fields were organic chemistry and
pharmacology Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemica ...
. He left Iran in 1979 following the regime change in the country and settled in the US where he continued his academic studies.


Early life and education

Lalezari was born in Hamadan on 4 July 1930. He was the eldest of four siblings. He received a degree in pharmacology from the University of Tehran. He obtained his PhD in pharmacology from his alma mater in 1951. He also received a PhD in organic chemistry from the University of Sorbonne in 1953. He carried out his post-doctorate studies in organic chemistry at the same institution in 1954.


Career and activities

Following his graduation, Lalezari joined the University of Tehran where he served as the chair of the chemistry department (1970–1978) and the dean of the pharmacology faculty (1973–1979). In 1964 he was promoted to a professorship in organic chemistry. He was named as the chair of the Iranian Pharmaceutical Association in 1975 which he held until 1979. In 1976 he was made a member of the Iranian Royal Academy of Sciences. In 1977 he established the Institute at Medicinal Plants at the University of Tehran which he headed until 1979. He had to leave Iran due to the establishment of an Islamic government in February 1979 and continued his academic studies in New York City where he worked at the
Montefiore Medical Center Montefiore Medical Center is a premier academic medical center and the primary teaching hospital of the Albert Einstein College of Medicine in the Bronx, New York City. Its main campus, the Henry and Lucy Moses Division, is located in the Norwoo ...
and Albert Einstein College of Medicine. He served as the director of medicinal chemistry in the latter. Lalezari was part of the Iranian Jewish delegation led by Moussa Kermanian who met with President Jimmy Carter in 1980. The goal of the meeting was to facilitate the migration of Iranian Jews to the US. He was a member of the American Jewish Federation and the Maccabee Foundation based in New York. In 2006 Lalezari retired from academic life.


Patents and work

Lalezari had numerous
patents A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention."A p ...
which he obtained between February 1977 and May 2015, including treatments for
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
using gene therapy methodologies. Some of these patents were taken jointly by him and his brother Parviz. Iraj Lalezari discovered the
hemoglobin A1C Glycated hemoglobin, also known as HbA1c, glycohemoglobin, hemoglobin A1c, A1C, is a form of hemoglobin (Hb) that is chemically linked to a sugar. Most monosaccharides, including glucose, galactose and fructose, spontaneously (i.e. non-enzymat ...
test which has been used in many countries to diagnose diabetes. He also invented some compounds of
fluoride Fluoride (). According to this source, is a possible pronunciation in British English. is an inorganic, monatomic anion of fluorine, with the chemical formula (also written ), whose salts are typically white or colorless. Fluoride salts typ ...
and selenium.


Later years, personal life and death

Lalezari was married and had two sons. Following his retirement he settled in Colorado and continued his studies at his home laboratory. In 2010 he joined Cell Viable, a company that develops and produces skincare products. He died in
Boulder, Colorado Boulder is a home rule city that is the county seat and most populous municipality of Boulder County, Colorado, United States. The city population was 108,250 at the 2020 United States census, making it the 12th most populous city in Color ...
, on 31 July 2019. He was buried at the Green Mountain Cemetery in Boulder on 2 August.


Awards

Lalezari was the recipient of the Lavoisier Medal which was granted to him in 1954 by the French Chemical Society. He was also awarded by the Shah
Mohammad Reza Pahlavi , title = Shahanshah Aryamehr Bozorg Arteshtaran , image = File:Shah_fullsize.jpg , caption = Shah in 1973 , succession = Shah of Iran , reign = 16 September 1941 – 11 February 1979 , coronation = 26 October ...
and Empress Farah Pahlavi for his outstanding studies.


References

{{DEFAULTSORT:Lalezari, Iraj 20th-century chemists 21st-century American chemists 1930 births 2019 deaths Iranian Jews Exiles of the Iranian Revolution in the United States People of Pahlavi Iran Iranian chemists Academic staff of the University of Tehran University of Tehran alumni Iranian pharmacologists University of Paris alumni People from Hamadan Albert Einstein College of Medicine faculty American inventors Iranian academic administrators