''Iotapapillomavirus'' is a genus of

viruses A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's ...

, in the family ''

Papillomaviridae ''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected ...

''. Rodents serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: cutaneous lesions and benign skin tumours, such as

papillomas A papilloma (plural papillomas or papillomata) ('' papillo-'' + '' -oma'') is a benign epithelial tumor growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection c ...

and

keratoacanthomas Keratoacanthoma (KA) is a common low-grade (unlikely to metastasize or invade) rapidly-growing skin tumour that is believed to originate from the hair follicle (pilosebaceous unit) and can resemble squamous cell carcinoma. The defining characteris ...

Taxonomy

The following two species are assigned to the genus: * ''

Iotapapillomavirus 1 ''Iotapapillomavirus'' is a genus of viruses, in the family ''Papillomaviridae ''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, tradition ...

'' * ''

Iotapapillomavirus 2 ''Iotapapillomavirus'' is a genus of viruses, in the family ''Papillomaviridae''. Rodents serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: cutaneous lesions and benign skin tumours, such a ...

Structure

Viruses in ''Iotapapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Rodents serve as the natural host. Transmission routes are contact.

References

External links

ICTV Report ''Papillomaviridae''

{{Taxonbar, from=Q18819939 Papillomavirus Virus genera