Iodobenzamide (IBZM or iolopride) is a pharmaceutical drug used for diagnostic purposes. It is a
dopamine antagonist and it can be used by
nuclear medicine physicians as a
radioactive tracer for
SPECT
Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. It is very similar to conventional nuclear medicine planar imaging using a gamma camera (that is, ...
where the radioactive
isotope is
iodine-123 or
iodine-125
Iodine-125 (125I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors. ...
.
The main purpose of a brain study with IBZM is the differentiation of
Parkinson's disease from other
neurodegenerative diseases such as
Lewy Body dementia and
multiple system atrophy
Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by autonomic dysfunction, tremors, slow movement, muscle rigidity, and postural instability (collectively known as parkinsonism) and ataxia. This is caused by progr ...
.
References
Radiopharmaceuticals
Benzamides
Iodoarenes
Phenols
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