An intracameral injection is usually of an
antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...
into the
anterior chamber of the eyeball to prevent
endophthalmitis
Endophthalmitis is inflammation of the interior cavity of the eye, usually caused by infection. It is a possible complication of all intraocular surgeries, particularly cataract surgery, and can result in loss of vision or loss of the eye itself ...
caused by an infection of the eye that can occur after
cataract surgery. The
Food and Drug Administration (FDA) has not approved antibiotics for this use and it is considered 'off-label'. Concerns about this procedure contributing to increasing numbers of
antibiotic resistant bacteria
A list of antibiotic resistant bacteria is provided below. These bacteria have shown antibiotic resistance (or antimicrobial resistance).
Enzyme NDM-1 (New Delhi Metallo-beta-lactamase-1)
NDM-1 is an enzyme that makes bacteria resistant to a ...
have been expressed.
In the UK, Aprokam cefuroxime has been approved for use in intracameral injections.
Intracameral injection of
recombinant tissue plasminogen activator (r-TPA) has been found to be effective in treating the development of
fibrin
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platele ...
intraocularly after the development of endophthalmitis.
References
Eye diseases
Medical emergencies
Ophthalmic drug administration
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