epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...

, particularly in the discussion of

infectious disease dynamics Mathematical models can project how infectious diseases progress to show the likely outcome of an epidemic (including in plants) and help inform public health and plant health interventions. Models use basic assumptions or collected statistics a ...

(mathematical modeling of disease spread), the infectious period is the time interval during which a

host A host is a person responsible for guests at an event or for providing hospitality during it. Host may also refer to: Places * Host, Pennsylvania, a village in Berks County People *Jim Host (born 1937), American businessman * Michel Host ...

(individual or patient) is infectious, i.e. capable of directly or indirectly transmitting pathogenic infectious agents or pathogens to another susceptible host. The infectious period can start before, during or after the onset of symptoms, and it may stop before or after the symptoms stop showing. It is also known in the literature by a variety of synonymous terms such as the infective period, the period of infectiousness, communicability period, the period of communicability, contagious period, the period of contagiousness, transmission period or transmissibility period. The degree of infectiousness is not constant but varies through the infectious period. When pathogens encounter a

susceptible individual In epidemiology a susceptible individual (sometimes known simply as a susceptible) is a member of a population who is at risk of becoming infected by a disease. Susceptible individuals Susceptibles have been exposed to neither the wild strain ...

and enter his or her body, it is called the ''exposure moment'', and the individual turns into a

for those pathogens. After entering a host's body (which marks the beginning of the infection process), pathogens usually require time to multiply or replicate at their favorite site in the body (for example, the Hepatitis virus multiplies in the liver). After a certain time period, the pathogens become numerous enough so that the host is now able to transmit them into the environment. This marks the end of the '' latent period'' (''pre-infectious period'') and simultaneously the beginning of the infectious period. As the disease becomes more severe, infectiousness increases. Meanwhile the host's body mounts immune responses to contain or eradicate the pathogens, and after a certain period of time, it may achieve that goal. The quantity of pathogens in the host's body become sufficiently low so that the host is no longer capable of transmitting the disease. This usually marks the end of the infectious period, even though for some diseases such as Ebola, the virus continues to be present in the body fluids of the survivor. By contrast, if the host's body cannot recover from a potentially deadly infection, the host will die. Even after death, the infectious period might not be over. For example, the dead body of an individual who died of Ebola remains very infectious for up to a week. A related concept is the ''shedding period'', which is the time interval during which a host or patient excretes the pathogenic organism through saliva, urine, feces or other bodily fluids. Shedding period usually coincides with the infectious period and used as its synonym. For viral infections, ''

viral load Viral load, also known as viral burden, is a numerical expression of the quantity of virus in a given volume of fluid, including biological and environmental specimens. It is not to be confused with viral titre or viral titer, which depends on the ...

'' and ''

viral shedding Viral shedding is the expulsion and release of virus progeny following successful reproduction during a host (biology), host cell (biology), cell infection. Once replication has been completed and the host cell is exhausted of all resources in ma ...

'' are important related concepts. Viral load refers to the quantity of

virion A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...

s (individual virus particles) in a given bodily fluid like blood, saliva, urine, etc. at different moments after infection. Viral shedding refers to the event when a host releases pathogens into his surroundings. Together these two factors influence how much and how long pathogens will be released among a population from an infected individual, two important metrics to measure the infectiousness of a disease. If the infectious period starts before the onset of the symptoms of the disease (i.e. the end of the ''

incubation period Incubation period (also known as the latent period or latency period) is the time elapsed between exposure to a pathogenic organism, a chemical, or radiation, and when symptoms and signs are first apparent. In a typical infectious disease, the i ...

''), then

asymptomatic carrier An asymptomatic carrier is a person or other organism that has become infected with a pathogen, but shows no signs or symptoms. Although unaffected by the pathogen, carriers can transmit it to others or develop symptoms in later stages of the d ...

s can unwittingly spread the disease in the community.

References

{{Concepts in infectious disease Infectious diseases Epidemiology

See also

References