''Anamirta cocculus'' ( mr, काकमारी) is a

Southeast Asia Southeast Asia, also spelled South East Asia and South-East Asia, and also known as Southeastern Asia, South-eastern Asia or SEA, is the geographical United Nations geoscheme for Asia#South-eastern Asia, south-eastern region of Asia, consistin ...

n and Indian

climbing plant A vine (Latin ''vīnea'' "grapevine", "vineyard", from ''vīnum'' "wine") is any plant with a growth habit of trailing or scandent (that is, climbing) stems, lianas or runners. The word ''vine'' can also refer to such stems or runners themselve ...

. Its

fruit In botany, a fruit is the seed-bearing structure in flowering plants that is formed from the ovary after flowering. Fruits are the means by which flowering plants (also known as angiosperms) disseminate their seeds. Edible fruits in particu ...

is the source of

picrotoxin Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François Guillaume Boullay (1777–1869) in 1812. The name "picrotoxin" is a combination of the Gree ...

, a

poison Poison is a chemical substance that has a detrimental effect to life. The term is used in a wide range of scientific fields and industries, where it is often specifically defined. It may also be applied colloquially or figuratively, with a broa ...

ous compound with stimulant properties. The plant is large-stemmed (up to 10 cm in diameter); the bark is "corky gray" with white wood. The "small, yellowish-white, sweet-scented" flowers vary between 6 and 10 millimeters across; the fruit produced is a

drupe In botany, a drupe (or stone fruit) is an indehiscent fruit in which an outer fleshy part (exocarp, or skin, and mesocarp, or flesh) surrounds a single shell (the ''pit'', ''stone'', or '' pyrena'') of hardened endocarp with a seed (''kernel'') ...

, "about 1 cm in diameter when dry".

Chemical substances

Fishberry (Anamirta cocculus) fruits closeup ruled

The stem and the roots contain

quaternary The Quaternary ( ) is the current and most recent of the three periods of the Cenozoic Era in the geologic time scale of the International Commission on Stratigraphy (ICS). It follows the Neogene Period and spans from 2.58 million years ...

alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...

s, such as

berberine Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as ''Berberis vulgaris'' (barberry), ''Berberis aristata'' (tree turmeric), ''Mahonia aquifolium'' (Oregon grape), ''Hydra ...

palmatine Palmatine is a protoberberine alkaloid found in several plants including ''Phellodendron amurense'', ''Coptis Chinensis'' (Rhizoma coptidis, chinese goldthread) and '' Corydalis yanhusuo'', ''Tinospora cordifolia'' (gurjo, heart-leaved moonseed), ...

magnoflorine ''(S)-''Magnoflorine is a quaternary benzylisoquinoline alkaloid (BIA) of the aporphine structural subgroup which has been isolated from various species of the family Menispermaceae, such as ''Pachygone ovata,'' '' Sinomenium acutum,'' and ''Cissa ...

and

columbamine Columbamine is a Chemical substance, chemical with the Chemical formula, molecular formula . It is an Organic chemistry, organic heterotetracyclic compound and a berberine alkaloid. Columbamine can be also called dehydroisocorypalmine. It has a ...

. The seeds deliver

, a

sesquiterpene Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many unique combinations. Biochemical modificatio ...

, while the seed shells contain the tertiary alkaloids menispermine and paramenispermine.

Uses

Its crushed seeds are an effective

pediculicide The treatment of human lice is the removal of head lice parasites from human hair. It has been debated and studied for centuries. However, the number of cases of human louse infestations (or pediculosis) has increased worldwide since the mid-1960s, ...

(anti-

lice Louse ( : lice) is the common name for any member of the clade Phthiraptera, which contains nearly 5,000 species of wingless parasitic insects. Phthiraptera has variously been recognized as an order, infraorder, or a parvorder, as a result o ...

) and are also traditionally used to stun fish or as a

pesticide Pesticides are substances that are meant to control pests. This includes herbicide, insecticide, nematicide, molluscicide, piscicide, avicide, rodenticide, bactericide, insect repellent, animal repellent, microbicide, fungicide, and lampri ...

. In

pharmacology Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemica ...

, it is known as Cocculus Indicus. Although poisonous, hard multum is a preparation made from ''Cocculus Indicus'', etc., once used (by 19th century brewers) to impart a more intoxicating quality ("giddiness") to

beer Beer is one of the oldest and the most widely consumed type of alcoholic drink in the world, and the third most popular drink overall after water and tea. It is produced by the brewing and fermentation of starches, mainly derived from ce ...

than provided by the alcoholic content alone.

Charles Dickens Charles John Huffam Dickens (; 7 February 1812 – 9 June 1870) was an English writer and social critic. He created some of the world's best-known fictional characters and is regarded by many as the greatest novelist of the Victorian e ...

referred to those engaging in such practices as "brewers and beer-sellers of low degree,... who do not understand the wholesome policy of selling wholesome beverage." Although appearing in many

homeopathic Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a dise ...

volumes and at least two brewers' guides, the use of such preparations was outlawed in England, during the mid-19th century, with fines of £500 for sale and £200 for use of the drug. The wood of the plant is used for

fuel A fuel is any material that can be made to react with other substances so that it releases energy as thermal energy or to be used for work. The concept was originally applied solely to those materials capable of releasing chemical energy but ...

and

carving Carving is the act of using tools to shape something from a material by scraping away portions of that material. The technique can be applied to any material that is solid enough to hold a form even when pieces have been removed from it, and ...

Common names

The

English English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national ide ...

common names are Indian berry, fishberry, or Levant nut (both referring to the

dried Drying is a mass transfer process consisting of the removal of water or another solvent by evaporation from a solid, semi-solid or liquid. This process is often used as a final production step before selling or packaging products. To be consider ...

fruit, and to the plant by

synecdoche Synecdoche ( ) is a type of metonymy: it is a figure of speech in which a term for a part of something is used to refer to the whole (''pars pro toto''), or vice versa (''totum pro parte''). The term comes from Greek . Examples in common Engl ...

) and coca de Levante in

Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Cana ...

; it is variously known as ligtang, aria (

Mindanao Mindanao ( ) ( Jawi: مينداناو) is the second-largest island in the Philippines, after Luzon, and seventh-most populous island in the world. Located in the southern region of the archipelago, the island is part of an island group of ...

), bayati ( Tagalog), and variations thereof throughout its natural distribution (the

Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...

East India East India is a region of India consisting of the Indian states of Bihar, Jharkhand, Odisha and West Bengal and also the union territory of the Andaman and Nicobar Islands. The region roughly corresponds to the historical region of Magadh ...

Malaysia Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two r ...

, and

New Guinea New Guinea (; Hiri Motu Hiri Motu, also known as Police Motu, Pidgin Motu, or just Hiri, is a language of Papua New Guinea, which is spoken in surrounding areas of Port Moresby (Capital of Papua New Guinea). It is a simplified version of ...

). The name "fishberry" comes from the use of the dried fruit as a method of

fishing Fishing is the activity of trying to catch fish. Fish are often caught as wildlife from the natural environment, but may also be caught from stocked bodies of water such as ponds, canals, park wetlands and reservoirs. Fishing techniques inclu ...

, in which the fish is "stupified and captured"; this method, however, is considered "unsportsmanlike".

References

{{Taxonbar, from=Q2007832 Tropical flora Medicinal plants of Asia Herbal and fungal stimulants Menispermaceae