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Inadine is an
iodine Iodine is a chemical element with the symbol I and atomic number 53. The heaviest of the stable halogens, it exists as a semi-lustrous, non-metallic solid at standard conditions that melts to form a deep violet liquid at , and boils to a vi ...
-containing non-sticky surgical dressing consisting of a knitted
viscose Rayon is a semi-synthetic fiber, made from natural sources of regenerated cellulose, such as wood and related agricultural products. It has the same molecular structure as cellulose. It is also called viscose. Many types and grades of viscose ...
fabric with a
polyethylene glycol Polyethylene glycol (PEG; ) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular we ...
base that contains and slowly releases the antiseptic
povidone-iodine Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. It may a ...
(PVP-1). It is applied to superficial wounds. It is a widely available dressing produced by Systagenix.


Structure and function

Inadine is an
iodine Iodine is a chemical element with the symbol I and atomic number 53. The heaviest of the stable halogens, it exists as a semi-lustrous, non-metallic solid at standard conditions that melts to form a deep violet liquid at , and boils to a vi ...
-containing non-sticky surgical dressing consisting of a knitted
viscose Rayon is a semi-synthetic fiber, made from natural sources of regenerated cellulose, such as wood and related agricultural products. It has the same molecular structure as cellulose. It is also called viscose. Many types and grades of viscose ...
fabric with a
polyethylene glycol Polyethylene glycol (PEG; ) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular we ...
base that contains and slowly releases the antiseptic
povidone-iodine Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. It may a ...
(PVP-1). It is a topical wound dressing and is considered suitable for superficial wounds. The rate of release of iodine is dependent on the amount of
moisture Moisture is the presence of a liquid, especially water, often in trace amounts. Small amounts of water may be found, for example, in the air (humidity), in foods, and in some commercial products. Moisture also refers to the amount of water vapo ...
from the wound. The dressing is thin, and comes sandwiched between backing papers, from which it is peeled off. Once applied directly to a recently cleaned wound it has the ability to absorb some
moisture Moisture is the presence of a liquid, especially water, often in trace amounts. Small amounts of water may be found, for example, in the air (humidity), in foods, and in some commercial products. Moisture also refers to the amount of water vapo ...
or blood from the wound. As the iodine is used up, the dressing loses colour and becomes white. It is typically held in place using gauze and then bandage material. The polyethylene glycol provides a moist environment allowing the iodine to reach the wound. After a few days the dressing has a tendency to dry out, and must be changed often. Left on too long, it can engage with wound tissue and wound secretions when drier, and be more difficult to remove. This tendency to adhere to
wounds A wound is a rapid onset of injury that involves lacerated or punctured skin (an ''open'' wound), or a contusion (a ''closed'' wound) from blunt force trauma or compression. In pathology, a ''wound'' is an acute injury that damages the epider ...
is usually resolved by soaking the wound for a few minutes with
normal saline Saline (also known as saline solution) is a mixture of sodium chloride (salt) and water. It has a number of uses in medicine including cleaning wounds, removal and storage of contact lenses, and help with dry eyes. By injection into a vein it ...
. Inadine is inexpensive, well tolerated and is a widely available dressing produced by Systagenix.


History

Iodine was first suggested as a dressing by John Davies in 1839 and had been evaluated by
Robert Koch Heinrich Hermann Robert Koch ( , ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera (though the Vibrio ...
and
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named afte ...
. E. Vallin had proposed the antimicrobial property of iodine in 1882. Until at least the 1950s, it was usual to see tinctures of iodine as an essential component of the medicine cabinet. Local pain, irritation and orange-brown staining of the skin, however, limited its use. Later formulations were developed which were less painful and their use has become widespread. With the exception of the United States, Inadine has been available in several countries since the 1980s. It was previously made by
Johnson & Johnson Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...
.


References


External links

*{{Youtube, iTEs6jD5aCA First aid Medical equipment