Iminoaspartic acid (also known as iminosuccinate or iminoaspartate) is a dicarboxylic acid in the biosynthesis of

nicotinic acid Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variet ...

. It is synthesised by the oxidation of

aspartate Aspartic acid (symbol Asp or D; the ionic form is known as aspartate), is an α-amino acid that is used in the biosynthesis of proteins. Like all other amino acids, it contains an amino group and a carboxylic acid. Its α-amino group is in the pro ...

and is condensed by

quinolinate synthase Quinolinate synthase (, ''NadA'', ''QS'', ''quinolinate synthetase'') is an enzyme with systematic name ''glycerone phosphate:iminosuccinate alkyltransferase (cyclizing)''. This enzyme catalyses the following chemical reaction : glycerone phosph ...

with

glycerone phosphate Dihydroxyacetone phosphate (DHAP, also glycerone phosphate in older texts) is the anion with the formula HOCH2C(O)CH2OPO32-. This anion is involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis.Nelson, D. L.; Co ...

to form

quinolinic acid Quinolinic acid (abbreviated QUIN or QA), also known as pyridine-2,3-dicarboxylic acid, is a dicarboxylic acid with a pyridine backbone. It is a colorless solid. It is the biosynthetic precursor to niacin. Quinolinic acid is a downstream produ ...

References

{{reflist Dicarboxylic acids Imines