Imidazolone
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Imidazolones are a family of
heterocyclic compound A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and ...
s, the parents of which have the formula OC(NH)2(CH)2. Two
isomer In chemistry, isomers are molecules or polyatomic ions with identical molecular formulae – that is, same number of atoms of each element – but distinct arrangements of atoms in space. Isomerism is existence or possibility of isomers. Iso ...
s are possible, depending on the location of the carbonyl (CO) group. The NH groups are nonadjacent. A common route to imidazol-2-ones involves condensation of ureas and
acyloin Acyloins or α-hydroxy ketones are a class of organic compounds which all possess a hydroxy group adjacent to a ketone group. The name acyloin is derived from the fact that they are formally derived from reductive coupling of carboxylic acyl grou ...
s. Some are of interest in the pharmaceuticals.{{cite journal, journal=Chemistry of Heterocyclic Compounds, year=2015, volume=51, page=395–420 , title=Methods for the synthesis of 1-substituted 1H-imidazol-2(3H)-ones, first1=Maria M., last1=Antonova, first2=Vladimir V., last2=Baranov, first3=Angelina N., last3=Kravchenko, doi=10.1007/s10593-015-1716-3 4-Imidazolones arise from the condensation of
amidine Amidines are organic compounds with the functional group RC(NR)NR2, where the R groups can be the same or different. They are the imine derivatives of amides (RC(O)NR2). The simplest amidine is formamidine, HC(=NH)NH2. Examples of amidines includ ...
s with 1,2-dicarbonyls such as
glyoxal Glyoxal is an organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of ...
.


References

Imidazoles