Integral membrane protein 2B (ITM2B or BRI2) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''ITM2B''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
''ITM2B'' or ''BRI2'' is a gene located on chromosome 13. The gene is connected to
familial Danish dementia and
familial British dementia causing amyloid and pre-filbrillar effects similar to those seen in
Alzheimer's
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...
.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
{{gene-13-stub