Interstate 88 may refer to either of two United States Interstate highways:
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Interstate 88 (Illinois)
Interstate 88 (I-88) is an Interstate Highway in the US state of Illinois that runs from an interchange with I-80 near Silvis and Moline to an interchange with I-290 and I-294 in Hillside, near Chicago. I-88 is long. This route is not ...
, running from East Moline to Hillside
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Interstate 88 (New York)
Interstate 88 (I-88) is an Interstate Highway located entirely within the US state of New York. Nominally signed as an east–west road as it has an even number, it extends for in a northeast–southwest direction from an interchange w ...
, running from Chenango to Rotterdam
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