I-270 may refer to:
*
Interstate 270 (disambiguation), one of several highways
*
Mikoyan-Gurevich I-270
The Mikoyan-Gurevich I-270 (Design Ж ("Zh") under Mikoyan-Gurevich's in-house designation sequence, USAF/DoD designation: Type 12) was a response to a Soviet Air Forces requirement in 1945 for a rocket-powered interceptor aircraft for the poi ...
, a cancelled Soviet interceptor aircraft
{{disambiguation