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No study has led to the isolation of true human sex pheromones, though various researchers have investigated the possibility of their existence. Sex pheromones are chemical ( olfactory) signals, pheromones, released by an organism to attract an individual, encourage it to mate with it, or perform some other function closely related with sexual reproduction. While humans are highly dependent upon visual cues, when in proximity, smells also play a role in sociosexual behaviors. An inherent difficulty in studying human pheromones is the need for cleanliness and odorlessness in human participants. Experiments have focused on three classes of putative human pheromones: axillary steroids, vaginal aliphatic acids, and stimulators of the vomeronasal organ. Axillary steroids are produced by the
testes A testicle or testis (plural testes) is the male reproductive gland or gonad in all bilaterians, including humans. It is homologous to the female ovary. The functions of the testes are to produce both sperm and androgens, primarily testost ...
, ovaries,
apocrine Apocrine () glands are a type of exocrine gland, which are themselves a type of gland, i.e. a group of cells specialized for the release of secretions. Exocrine glands secrete by one of three means: holocrine, merocrine and apocrine. In apocr ...
glands and
adrenal gland The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which ...
s. These chemicals are not biologically active until puberty when sex steroids influence their activity. The activity change during puberty suggest that humans communicate through odors. Several axillary steroids have been described as possible human pheromones:
androstadienol Androstadienol, or androsta-5,16-dien-3β-ol, is a 16-androstene class endogenous steroid, pheromone, and chemical intermediate to several other pheromones that is found in the sweat of both men and women. Androstadienol and androstadienone ...
,
androstadienone Androstadienone, or androsta-4,16-dien-3-one, is a 16-androstene class endogenous steroid that has been described as having potent pheromone-like activities in humans. The compound is synthesized from androstadienol by 3β-hydroxysteroid dehydro ...
,
androstenone Androstenone (5α-androst-16-en-3-one) is a 16-androstene class steroidal pheromone. It is found in boar's saliva, celery cytoplasm, and truffle fungus. Androstenone was the first mammalian pheromone to be identified. It is found in high concent ...
,
androstenol Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. It possesses a characteristic musk ...
, and
androsterone Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7 that of testosterone. Androsterone is a metabolite of tes ...
. Androstenol is the putative female pheromone. In a 1978 study by Kirk-Smith, people wearing surgical masks treated with androstenol or untreated were shown pictures of people, animals and buildings and asked to rate the pictures on attractiveness. Individuals with their masks treated with androstenol rated their photographs as being "warmer" and "more friendly". The best-known case study involves the synchronization of menstrual cycles among women based on unconscious odor cues, the '' McClintock effect'', named after the primary investigator,
Martha McClintock Martha Kent McClintock (born February 22, 1947) is an American psychologist best known for her research on human pheromones and her theory of menstrual synchrony. Her research focuses on the relationship that the environment and biology have upon ...
, of the University of Chicago. A group of women were exposed to a whiff of perspiration from other women. Depending on the time in the month the sweat was collected (before, during, or after ovulation), there was an association with the recipient woman's menstrual cycle to speed up or slow down. The 1971 study proposed two types of pheromone involved: "One, produced prior to ovulation, shortens the ovarian cycle; and the second, produced just at ovulation, lengthens the cycle". However, recent studies and reviews of the methodology have called the validity of her results into question. A 2013 meta-review of existing studies showed that the syncing of ovarian cycles likely did not exist. Androstenone is postulated to be secreted only by men as an attractant for women and is also thought to affect their mood positively. It seems to have different effects on women, depending on where a female is in her menstrual cycle, with the highest sensitivity to it during ovulation. In 1983, study participants exposed to androstenone were shown to undergo changes in skin conductance. Androstenone has been found to be perceived as more pleasant to women at a woman’s time of ovulation. It is hypothesized that this may be a way for a male to detect an ovulating female who would be more willing to be involved in sexual interaction. As of 2014, no human pheromones were known.Jacob 2005.


See also

* * * Sexual attraction


References


Bibliography

* * Jacob, Tim J.C. (2005) [1999
A critical review of the evidence for the existence (1) human pheromones and (2) a functional vomeronasal organ (VNO) in humans
School of Biosciences, Cardiff University {{Pheromones and pherines Human pheromones Human reproduction Human sexuality Pheromones Sexual reproduction Sexual attraction