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Homer William Smith (January 2, 1895 – March 25, 1962) was an American
physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
and
science writer Science journalism conveys reporting about science to the public. The field typically involves interactions between scientists, journalists, and the public. Origins Modern science journalism dates back to '' Digdarshan'' (means showing the d ...
known for his experiments on the
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blo ...
and philosophical writings on natural history and the theory of
evolution Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
.


Biography

Smith was born in
Denver Denver () is a consolidated city and county, the capital, and most populous city of the U.S. state of Colorado. Its population was 715,522 at the 2020 census, a 19.22% increase since 2010. It is the 19th-most populous city in the Unit ...
, and three years later, his family moved to
Cripple Creek, Colorado Cripple Creek is a statutory city that is the county seat of Teller County, Colorado, United States. The city population was 1,155 at the 2020 United States Census. Cripple Creek is a former gold mining camp located southwest of Colorado Sprin ...
, which was included in both the Cripple Creek miners' strike of 1894 and the Colorado Labor Wars of 1903–04. He had a stutter from about the age of five, to which he attributes his introspectiveness. Smith's mother died by the time he was seven; he had five older siblings at the time, the oldest of which was 26. Smith describes his father as "of the generation that had one foot still planted in
religious Religion is usually defined as a social- cultural system of designated behaviors and practices, morals, beliefs, worldviews, texts, sanctified places, prophecies, ethics, or organizations, that generally relates humanity to supernatur ...
tradition, the other planted in irreligious
rationalism In philosophy, rationalism is the epistemological view that "regards reason as the chief source and test of knowledge" or "any view appealing to reason as a source of knowledge or justification".Lacey, A.R. (1996), ''A Dictionary of Philosophy' ...
. ... For his mixed sentiment and skepticism my father paid off his conscience by generous hospitality, and any minister of any gospel was welcome at his table." At the age of eleven, while Smith had the
measles Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than , cough, ...
, his father built him a shed in which he could conduct scientific experiments; these involved chemistry and
microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...
, as well as the use of a
vacuum pump A vacuum pump is a device that draws gas molecules from a sealed volume in order to leave behind a partial vacuum. The job of a vacuum pump is to generate a relative vacuum within a capacity. The first vacuum pump was invented in 1650 by Otto ...
,
telegraph Telegraphy is the long-distance transmission of messages where the sender uses symbolic codes, known to the recipient, rather than a physical exchange of an object bearing the message. Thus flag semaphore is a method of telegraphy, whereas ...
, static machine,
X-ray tube An X-ray tube is a vacuum tube that converts electrical input power into X-rays. The availability of this controllable source of X-rays created the field of radiography, the imaging of partly opaque objects with penetrating radiation. In contrast ...
, and
Tesla coil A Tesla coil is an electrical resonant transformer circuit designed by inventor Nikola Tesla in 1891. It is used to produce high-voltage, low- current, high-frequency alternating-current electricity. Tesla experimented with a number of differen ...
. He also dissected cats, which fueled his interest for biology and diminished his faith in
anthropocentrism Anthropocentrism (; ) is the belief that human beings are the central or most important entity in the universe. The term can be used interchangeably with humanocentrism, and some refer to the concept as human supremacy or human exceptionalism. ...
. As a result of the apathy he felt following the
sinking of the RMS Titanic The sank in the early morning hours of 15 April 1912 in the North Atlantic Ocean, four days into her maiden voyage from Southampton to New York City. The largest ocean liner in service at the time, ''Titanic'' had an estimated 2,224 pe ...
on April 15, 1912, he set out on a philosophical quest of reading and writing with a renewed focus towards scholarship. Smith received his
D.Sc Doctor of Science ( la, links=no, Scientiae Doctor), usually abbreviated Sc.D., D.Sc., S.D., or D.S., is an academic research degree awarded in a number of countries throughout the world. In some countries, "Doctor of Science" is the degree used f ...
in 1921 from Johns Hopkins University School of Hygiene and Public Health. From 1928 until his retirement in 1961 he was the Professor of Physiology and Director of the Physiological Laboratories at
New York University School of Medicine NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of ...
. Smith was a leader in the field of
renal physiology Renal physiology (Latin ''rēnēs'', "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, ...
. His elegant experiments on the kidney in the 1930s proved beyond any doubt that it operated according to physical principles, both as a filter and a secretory organ, eliminating the last vestige of
vitalism Vitalism is a belief that starts from the premise that "living organisms are fundamentally different from non-living entities because they contain some non-physical element or are governed by different principles than are inanimate things." Wher ...
in physiology. He used inulin (at the same time as A. N. Richards) to measure how much kidney filtrate is formed. His book ''The Kidney: Structure and Function in Health and Disease'' (1951) was an authoritative summary of what was known at that time. ''Komongo or, the Lungfish and the Padre'' (1932) takes place in the
Suez Canal The Suez Canal ( arz, قَنَاةُ ٱلسُّوَيْسِ, ') is an artificial sea-level waterway in Egypt, connecting the Mediterranean Sea to the Red Sea through the Isthmus of Suez and dividing Africa and Asia. The long canal is a popula ...
where a scientist returning to the United States with a cargo of lungfish for kidney experiments delivers a monologue to an Anglican Minister on how
evolution Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
shapes organisms. The book, after being personally rejected by
Alfred A. Knopf Alfred A. Knopf, Inc. () is an American publishing house that was founded by Alfred A. Knopf Sr. and Blanche Knopf in 1915. Blanche and Alfred traveled abroad regularly and were known for publishing European, Asian, and Latin American writers i ...
, was accepted by
Viking Press Viking Press (formally Viking Penguin, also listed as Viking Books) is an American publishing company owned by Penguin Random House. It was founded in New York City on March 1, 1925, by Harold K. Guinzburg and George S. Oppenheim and then acquir ...
. It was became a
Book of the Month Book of the Month (founded 1926) is a United States subscription-based e-commerce service that offers a selection of five to seven new hardcover books each month to its members. Books are selected and endorsed by a panel of judges, and members ch ...
, was included in '' The Woollcott Reader'' (1935), and republished as a Pocket Overseas Edition for the troops during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great power ...
, and then made a monthly selection by the Natural History Book Club. For the latter republication, the book had to be reset, as the original plates had been donated during the metal shortages of 1943–44. Smith desired to make changes to the book, which the publisher gave him a week to make. The manuscript for ''Man and His Gods'' (1952), which Smith describes as "a simple story of man's changing ideas about himself and his place in nature," was declined by several publishers and reduced from about 275,000 to 250,000 words before it was accepted by
Little, Brown and Company Little, Brown and Company is an American publishing company founded in 1837 by Charles Coffin Little and James Brown in Boston. For close to two centuries it has published fiction and nonfiction by American authors. Early lists featured Emily ...
. The publisher made further cuts for length, which Smith approved of. It considers "man's ideas about the supernatural in the perspective of the evolution of western theology and philosophy from the ancient Egyptians to the nineteenth century", culminating in
Darwin's theory of evolution Darwinism is a theory of biological evolution developed by the English naturalist Charles Darwin (1809–1882) and others, stating that all species of organisms arise and develop through the natural selection of small, inherited variations that ...
and the reaction to it, including the thoughts of
Thomas Henry Huxley Thomas Henry Huxley (4 May 1825 – 29 June 1895) was an English biologist and anthropologist specialising in comparative anatomy. He has become known as "Darwin's Bulldog" for his advocacy of Charles Darwin's theory of evolution. The stori ...
and the relationship of modern thought to that of pre-evolutionist philosophers
John Locke John Locke (; 29 August 1632 – 28 October 1704) was an English philosopher and physician, widely regarded as one of the most influential of Enlightenment thinkers and commonly known as the "father of liberalism". Considered one of ...
,
David Hume David Hume (; born David Home; 7 May 1711 NS (26 April 1711 OS) – 25 August 1776) Cranston, Maurice, and Thomas Edmund Jessop. 2020 999br>David Hume" '' Encyclopædia Britannica''. Retrieved 18 May 2020. was a Scottish Enlightenment ph ...
and
Immanuel Kant Immanuel Kant (, , ; 22 April 1724 – 12 February 1804) was a German philosopher and one of the central Enlightenment thinkers. Born in Königsberg, Kant's comprehensive and systematic works in epistemology, metaphysics, ethics, and ...
.
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theor ...
says in the foreword: ''From Fish to Philosopher'' (1953) explains how evolutionary history accounts for the seemingly bewildering mammalian kidney, in which water, salts, and small molecules are filtered from the blood into kidney tubules and then much of the water and salt and many of the small molecules are pumped back into the blood stream. He argues that vertebrates originated in fresh water, where water was drawn into their bodies by the
osmotic pressure Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane. It is also defined as the measure of the tendency of a solution to take in a pure ...
of their body fluids; their kidneys excreted the extra water while also retrieving their supply of small solutes. Smith served on the board of trustees of Science Service, now known as Society for Science & the Public, from 1952–1955. As a memorial to Smith in 1963 the New York Heart Association created the Homer W. Smith Award in Renal Physiology. Additionally, the American Society of Nephrology established The Homer Smith Award in 1964. The award is presented annually to an individual who has made outstanding contributions which fundamentally affect the science of nephrology, broadly defined, but not limited to, the pathobiology, cellular and molecular mechanisms and genetic influences on the functions and diseases of the kidney. Homer Smith was married to Margaret Wilson, who was the daughter of Lily and James Robert Wilson from Spring City, Tennessee. His son was Homer Wilson Smith.


Views on religion

Smith attacked
superstition A superstition is any belief or practice considered by non-practitioners to be irrational or supernatural, attributed to fate or magic, perceived supernatural influence, or fear of that which is unknown. It is commonly applied to beliefs ...
and was critical of religious ideas. He was
agnostic Agnosticism is the view or belief that the existence of God, of the divine or the supernatural is unknown or unknowable. (page 56 in 1967 edition) Another definition provided is the view that "human reason is incapable of providing sufficien ...
and an advocate of the
Christ myth theory The Christ myth theory, also known as the Jesus myth theory, Jesus mythicism, or the Jesus ahistoricity theory, is the view that "the story of Jesus is a piece of mythology", possessing no "substantial claims to historical fact". Alternatively ...
.


Publications

*''Kamongo, or The Lungfish and the Padre'' (1932) *''The Kidney: Structure and Function in Health and Disease'' (1951) *''Man and His Gods'' (1952) [wit
foreword
by Albert Einstein] *''From Fish to Philosopher'' (1953)


Quotes

* "What engineer, wishing to regulate the composition of the internal environment of the body on which the function of every bone, gland, muscle, and nerve depends, would devise a scheme that operated by throwing the whole thing out 16 times a day and rely on grabbing from it, as it fell to earth, only those precious elements which he wanted to keep?"


References

Footnotes Citations


Sources

*


Further reading

*Herbert Chasis, William Goldring. (1965). ''Homer William Smith: His Scientific and Literary Achievements''. New York University Press. *L. G. Navar. (2004)
''The Legacy of Homer W. Smith: Mechanistic Insights into Renal Physiology''
''
Journal of Clinical Investigation The ''Journal of Clinical Investigation'' is a twice-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation. Articles focus on the mechanism ...
'' 114 (8): 1048–1050. {{DEFAULTSORT:Smith, Homer William 1895 births 1962 deaths American agnostics American humanists American physiologists American science writers American skeptics Christ myth theory proponents Critics of Christianity Johns Hopkins Bloomberg School of Public Health alumni People from Denver Recipients of the Albert Lasker Award for Basic Medical Research New York University Grossman School of Medicine faculty Writers about religion and science