Hartmut Michel (; born 18 July 1948) is a German biochemist, who received the 1988 Nobel Prize in Chemistry for determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential to photosynthesis.

Education and early life

He was born on 18 July 1948 in Ludwigsburg. After compulsory military service, he studied biochemistry at the

University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-W� ...

, working for his final year at Dieter Oesterhelt's laboratory on ATPase activity of

halobacteria Haloarchaea (halophilic archaea, halophilic archaebacteria, halobacteria) are a class of the Euryarchaeota, found in water saturated or nearly saturated with salt. Halobacteria are now recognized as archaea rather than bacteria and are one of ...

Career and research

Hartmut later worked on the crystallisation of

membrane protein Membrane proteins are common proteins that are part of, or interact with, biological membranes. Membrane proteins fall into several broad categories depending on their location. Integral membrane proteins are a permanent part of a cell membrane ...

s - essential for their structure elucidation by

X-ray crystallography X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles ...

. He received the

Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...

jointly with Johann Deisenhofer and Robert Huber in 1988. Together with Michel and Huber, Deisenhofer determined the three-dimensional structure of a protein complex found in certain photosynthetic bacteria. This membrane protein complex, called a photosynthetic reaction center, was known to play a crucial role in initiating a simple type of photosynthesis. Between 1982 and 1985, the three scientists used

to determine the exact arrangement of the more than 10,000 atoms that make up the protein complex. Their research increased the general understanding of the mechanisms of photosynthesis, revealed similarities between the photosynthetic processes of plants and bacteria and established a methodology for crystallising membrane proteins. Since 1987 he has been director of the Molecular Membrane Biology department at the Max Planck Institute for Biophysics in

Frankfurt am Main Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its na ...

, Germany, and professor of biochemistry at the Goethe University Frankfurt.

Awards and honours

In 1986, he received the Gottfried Wilhelm Leibniz Prize of the

Deutsche Forschungsgemeinschaft The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germ ...

, which is the highest honour awarded in German research. In 1988, he received the Nobel Prize in Chemistry. He received the Bijvoet Medal at the

Bijvoet Center for Biomolecular Research The Bijvoet Centre for Biomolecular Research is a research institute at Utrecht University. The Bijvoet Centre performs research on the relation between the structure and function of biomolecules, including proteins and lipids, which play a role ...

of Utrecht University in 1989. In 1995 he became a member of the German Academy of Sciences Leopoldina. He also became a foreign member of the Royal Netherlands Academy of Arts and Sciences in 1995. He was elected a Foreign Member of the Royal Society (ForMemRS) in 2005.

References

External links

* {{DEFAULTSORT:Michel, Hartmut 1948 births Members of the European Molecular Biology Organization Foreign associates of the National Academy of Sciences Living people German biochemists Nobel laureates in Chemistry German Nobel laureates Gottfried Wilhelm Leibniz Prize winners Foreign Members of the Royal Society Foreign members of the Chinese Academy of Sciences Members of the Royal Netherlands Academy of Arts and Sciences Max Planck Society people Commanders Crosses of the Order of Merit of the Federal Republic of Germany Recipients of the Order of Merit of Baden-Württemberg Academic staff of Goethe University Frankfurt Scientists from Frankfurt Researchers of photosynthesis Bijvoet Medal recipients Members of the German Academy of Sciences Leopoldina University of Tübingen alumni Max Planck Institute directors