Hywel Davies (doctor)
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David Hywel Davies (16 August 1924 – December 2016) was a Welsh cardiologist and writer. He wrote extensively on a range of medical and scientific subjects.


Career

Born in Swansea, Wales in 1924, Davies attended Swansea Grammar School (now known as
Bishop Gore School The Bishop Gore School ( cy, Ysgol Esgob Gore) is a secondary school in Swansea in Wales, founded on 14 September 1682 by Hugh Gore (1613–1691), Bishop of Waterford and Lismore. It is situated in Sketty, close to Singleton Park and Swansea ...
) and gained a Meyricke Exhibition in chemistry at
Jesus College, Oxford Jesus College (in full: Jesus College in the University of Oxford of Queen Elizabeth's Foundation) is one of the constituent colleges of the University of Oxford in England. It is in the centre of the city, on a site between Turl Street, Ship St ...
. He interrupted his studies in 1943 to join the Royal Engineers, in which regiment he was commissioned and served in Italy, India and Malaya. Upon returning to Oxford in 1946, he changed his degree and started reading medicine. Davies undertook his clinical studies at Westminster Hospital, London, where he gained the Sturges Prize in clinical medicine and a BMA prize for his essay on Clinical Teaching in Relation to the Practice of Medicine. He qualified BM, BCh in 1952. After various appointments in paediatrics and general medicine, Davies specialised in cardiology and took up a residency at the University of Colorado Medical Center in Denver. After a year he was appointed by Dr Paul Wood as registrar at the National Heart Hospital and Institute of Cardiology in London. Subsequently he was senior registrar and senior lecturer at Guy's Hospital and was awarded the Carey-Coombs prize of the University of Bristol. Dr Davies graduated with a D.Phil. from
Jesus College, Oxford Jesus College (in full: Jesus College in the University of Oxford of Queen Elizabeth's Foundation) is one of the constituent colleges of the University of Oxford in England. It is in the centre of the city, on a site between Turl Street, Ship St ...
in 1965 with a thesis entitled ''Respiratory disturbances in congenital heart disease''. In 1967 he was invited to join the faculty of the
University of Colorado, Denver The University of Colorado Denver (CU Denver) is a public research university in Denver, Colorado. It is part of the University of Colorado system. History University of Colorado System Anschutz Medical Campus The University of Colorado create ...
, and was Chief of Cardiology at the VA Hospital in Denve


Personal life

Davies married his wife Lucette in 1955. The couple had one daughter, who lives in London. Dr Davies lived in
Sion, Switzerland , neighboring_municipalities= Ayent, Conthey, Grimisuat, Grône, Les Agettes, Nax, Nendaz, Saint-Léonard, Salins, Savièse, Vernamiège, Vex , twintowns = Sion (; german: Sitten ; it, Seduno; la, Sedunum) is a Swiss town, a mun ...
and devoted most of his time to writing. He died in December 2016.


Medical interests


The Hywel Davies chest deformity

Dr Davies gave the first comprehensive description in 1959 of the chest deformities which accompany congenital heart disease and their relationship to disturbed lung function. The typical barrel-shaped deformity accompanying the large ventricular septal defect was called the "Hywel Davies chest deformity" by Dr Paul Wood and was known as such for some years, and as the "Thorax of Davies" on the continen

He showed that it was the result of increased stiffness of the lungs due to high flow and pressure of blood in them. These observations of the relationship of the circulation to lung function were followed by a more general study of the causes of breathlessness in heart disease, which led to a series of papers in the 1960s and 70's analysing the interplay of chemical changes in the blood (acidity, oxygenation and carbon dioxide level), mechanical factors in the control of breathing in various forms of heart disease as well as in normal people. He was associated closely in those years with active and pioneering cardiac surgical programmes (Drs Henry Swan, George Pappas and Thomas Starzl in Denver, Sir Russell Brock and Mr Donald Ross at
Guy's Hospital Guy's Hospital is an NHS hospital in the borough of Southwark in central London. It is part of Guy's and St Thomas' NHS Foundation Trust and one of the institutions that comprise the King's Health Partners, an academic health science centre. ...
).


Cholesterol, heart disease and modern medicine

In the 1970s and 80's Dr. Davies became increasingly interested in coronary artery disease and its causes, for that now constituted the majority of his practice. He believes that medicine took a wrong turning when it elected to devote the bulk of its resources to studying
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
and to largely inconclusive clinical trials based on flawed statistical manipulation. He did not accept that elevated cholesterol levels were the main cause of coronary disease, nor that eating margarine or not eating eggs would have any beneficial effects. He emphasised that the beginnings of coronary disease could occur in childhood and that the first changes consisted of undue multiplication of cells in the inner lining of the coronary arteries, and that these had little to do with fats and cholesterol. He was given the opportunity to study these further in an accelerated human form when he was asked by Mr (now Sir) Terence English to join him at
Papworth Hospital Royal Papworth Hospital is a specialist heart and lung hospital, located on the Cambridge Biomedical Campus in Cambridgeshire, England. The Hospital is run by Royal Papworth Hospital NHS Foundation Trust. The hospital is a world-leading cardiot ...
, where he worked from 1986 to 1988 as consultant cardiologist to the heart transplant programme.


Vitamin D

During these years he became increasingly interested in the role of ionic calcium in the control of cell division, and the environmental causes of disturbance of calcium metabolism, especially excessive intakes of
calcium Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to ...
,
vitamin D Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects. In humans, the most important compounds in this group are vitamin D3 (c ...
and
phosphorus Phosphorus is a chemical element with the symbol P and atomic number 15. Elemental phosphorus exists in two major forms, white phosphorus and red phosphorus, but because it is highly reactive, phosphorus is never found as a free element on Ear ...
. He has pointed out in recent publications such as "The Child, The Environment and Coronary Heart Disease", the subtle inter-relationships that exist in the genesis of coronary disease, including pre-natal influences, infant feeding patterns, and the particular role of calcium and inflammation. The failure to recognise these, he believes, has been responsible for the lack of real progress in the understanding of heart disease as well as cancer, which is also an aberration of cell multiplication. He is much opposed to current attempts, mostly by non-clinicians, to increase the intake of Vitamin D without any consideration of its deleterious cardiovascular effects, which he sees as unwise and even dangerous. His singular views have recently been expressed in a self-published monograph entitled "Vitamin D in Disarray" where he calls into serious question the existence of widespread Vitamin D deficiency as well as the associations claimed between geographic latitude and various diseases such as multiple sclerosis and cancer.


Homeopathy

In the chapter "New Year's Aspirations and Alternative Medicine" from ''Uncle Ebe and Other Stories'', Davies asserts that much criticism of
alternative medicine Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
in general and
homoeopathy Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a dise ...
in particular is faulty. He suggests that large scale statistical analysis of the benefits of such treatments are impossible because "in homeopathy each individual is treated as unique, and no two patients receive the same medications for the same complaint" and so "the number of factors involved the decision making becomes so great that statistical comparisons are worthless". He goes onto argue that many homoeopathic sceptics ignore evidence from the field of materials science, stating that "the assumption that great dilutions of active principles imply the ultimate absence of useful properties is intuitively reasonable but is only an assumption and is probably wrong".


Other views

Davies disagrees that
global warming In common usage, climate change describes global warming—the ongoing increase in global average temperature—and its effects on Earth's climate system. Climate change in a broader sense also includes previous long-term changes to E ...
is the result of human activity and argues that the most pressing threat to humanity's future consists of pollution caused by the growth in the number of new chemical products that have found their way into the human food chain over the last half-century. Orthodox medical advice about diet has been wrong he believes, pointing to the increase in obesity and diabetes rates as evidence for this claim.


Bibliography

Books ''Modern Medicine'', Abelard, London 1977 ''The Child, its Environment, and the Development of Coronary Arterial Disease'', (in press) ''Understanding Cardiology'', (with W.P. Nelson), Butterworths, Boston and London 1978 ''Uncle Ebe and Other Stories'', The Memoir Club, Durham 2010 ''Vitamin D in Disarray'', self-published monograph, Sion 2010 Selected Articles Ailward D, Davies DH, Hecker R : ''Effects of Venostasin on Serum Cholesterol Levels''. Br Med J 1, 398, 1955. Davies H : ''Chest Deformities in Congenital Heart Disease'', Brit J Dis Chest 53, 151–155, 1959. Davies H, Williams JV, Wood P : ''Lung Stiffness in States of Abnormal Pulmonary Blood Flow and Pressure'', Brit Heart J 24, 129–138, 1962. Davies H : "On the Therapy of Coronary Artery Disease" (Editorial). Am J Med Sci 258, 371–373, 1969 Davies H : ''Symptoms in Congenital Heart Disease : Factors in Their Genesis and the Surgeon's Role in Their Alleviation'' Guy's Hosp Rep 118, 129–157, 1969. Davies H : ''Cerebral Blood Flow in Drugs and Cerebral Function'' Ed. WL Smith, CC Thomas, Springfield, 1970. Davies H : ''Coronary heart disease : the significance of coronary pathology in infancy and the role of mitogens such as Vitamin D'', Medical Hypotheses 1989 ; 30 : 179–185.


References

{{DEFAULTSORT:Davies, Hywel 1924 births 2016 deaths British cardiologists People educated at Bishop Gore School People from Sion, Switzerland University of Colorado Denver faculty