''Hypsitherium'' is an extinct genus of

Mesotheriidae Mesotheriidae ("Middle Beasts") is an extinct family of notoungulate mammals known from the Oligocene through the Pleistocene of South America. Mesotheriids were small to medium-sized herbivorous mammals adapted for digging. Characteristics M ...

that lived 4.0 to 3 million years ago, and is known from the Miocene to Pliocene Inchasi fossil locality in Bolivia. It was a scansorial herbivore, with its name meaning "high beast."

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