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''Hypoxis hemerocallidea'', the African star grass or African potato, is a
medicinal plant Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including Plant defense against her ...
in the
Hypoxidaceae Hypoxidaceae is a family of flowering plants, placed in the order Asparagales of the monocots. The APG IV system of 2016 (unchanged from the 1998, 2003, and 2009 versions) recognizes this family. The family consists of four genera totalling s ...
family. It is native to southern
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
from
South Africa South Africa, officially the Republic of South Africa (RSA), is the southernmost country in Africa. It is bounded to the south by of coastline that stretch along the South Atlantic and Indian Oceans; to the north by the neighbouring countri ...
as far north as
Mozambique Mozambique (), officially the Republic of Mozambique ( pt, Moçambique or , ; ny, Mozambiki; sw, Msumbiji; ts, Muzambhiki), is a country located in southeastern Africa bordered by the Indian Ocean to the east, Tanzania to the north, Malawi ...
and
Zimbabwe Zimbabwe (), officially the Republic of Zimbabwe, is a landlocked country located in Southeast Africa, between the Zambezi and Limpopo Rivers, bordered by South Africa to the south, Botswana to the south-west, Zambia to the north, and Mozam ...
. This plant is the best known member of this genus.


Medicinal uses

''Hypoxis'' is promoted as an
alternative medicine Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
treatment for
benign prostatic hyperplasia Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss o ...
, but research has found no evidence of beneficial effect. Additionally, one study suggests ''Hypoxis'' alters the activity of
cytochrome P450 Cytochromes P450 (CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are ...
, suggesting that it may interfere with the effectiveness of other drugs or supplements, such as
antiretroviral drug The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple ...
s.


References


External links

* Hypoxis hemerocallidea research University Kwazulu-Nata

* Hypoxis hemerocallidea South African National Biodiversity Institut

Hypoxis, hemerocallidea Flora of Southern Africa Medicinal plants of Africa Plants described in 1842 {{medicinal-plant-stub