Hygrine is a
pyrrolidine
Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH2)4NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most ...
alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...
, found mainly in
coca
Coca is any of the four cultivated plants in the family Erythroxylaceae, native to western South America. Coca is known worldwide for its psychoactive alkaloid, cocaine.
The plant is grown as a cash crop in the Argentine Northwest, Bolivia, Al ...
leaves (0.2%). It was first isolated by
Carl Liebermann
Carl Theodore Liebermann (23 February 1842 – 28 December 1914) was a German chemist and student of Adolf von Baeyer.
Life
Liebermann first studied at the University of Heidelberg where Robert Wilhelm Bunsen was teaching. He then joined the ...
in 1889 (along with a related compound
cuscohygrine
Cuscohygrine is a pyrrolidine alkaloid found in coca. It can also be extracted from plants of the family Solanaceae, including ''Atropa belladonna'' (deadly nightshade), ''Datura innoxia'' and ''Datura stramonium'' (jimson weed). Cuscohygrine usua ...
) as an alkaloid accompanying
cocaine
Cocaine (from , from , ultimately from Quechuan languages, Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly recreational drug use, used recreationally for its euphoria, euphoric effects. It is primarily obtained from t ...
in coca. Hygrine is extracted as a thick yellow oil, having a pungent taste and odor.
See also
*
Coca alkaloid
Coca alkaloids are the alkaloids found in the coca plant, ''Erythroxylum coca''.Variation of Alkaloid Content in Erythroxylum coca Leaves from Leaf Bud to Leaf Drop. Emanuel L. Johnson and Stephen D. Emche, Ann. Bot., 1994, volume 73, issue 6, page ...
s
*
Pseudotropine
Pseudotropine (3β-tropanol, ψ-tropine, 3-pseudotropanol, or PTO) is a derivative of tropane and an isomer of tropine. Pseudotropine can be found in the ''Coca'' plant along with several other alkaloids
See also
* Pseudotropine acyltransfe ...
*
Troparil
Troparil (also known as (–)-2β-Carbomethoxy-3β-phenyltropane, WIN 35,065-2, or β-CPT) is a stimulant drug used in scientific research. Troparil is a phenyltropane-based dopamine reuptake inhibitor (DRI) that is derived from methylecgonidine ...
References
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* {{cite web, title=USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. National Germplasm Resources Laboratory, Beltsville, Maryland. , url=http://sun.ars-grin.gov:8080/npgspub/xsql/duke/chemdisp.xsql?chemical=HYGRINE , archive-url=https://archive.today/20121211210941/http://sun.ars-grin.gov:8080/npgspub/xsql/duke/chemdisp.xsql?chemical=HYGRINE , url-status=dead , archive-date=December 11, 2012 , accessdate=July 15, 2005
Pyrrolidine alkaloids
Alkaloids found in Erythroxylum coca
Ketones