Hydroquinidine
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Dihydroquinidine (also called hydroquinidine) is an
organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. T ...
, a cinchona alkaloid closely related to
quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to '' Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal le ...
. The specific rotation is +226° in
ethanol Ethanol (abbr. EtOH; also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound. It is an alcohol with the chemical formula . Its formula can be also written as or (an ethyl group linked to a ...
at 2g/100 ml. A derivative of this molecule is used as
chiral ligand Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecu ...
in the AD-mix for
Sharpless dihydroxylation Sharpless asymmetric dihydroxylation (also called the Sharpless bishydroxylation) is the chemical reaction of an alkene with osmium tetroxide in the presence of a chiral quinine ligand to form a vicinal diol. The reaction has been applied to alk ...
. The substance is also a class Ia
antiarrhythmic Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of pharmaceuticals that are used to suppress abnormally fast rhythms (Tachycardia, tachycardias), such as atrial fibrillation, supraventricular tachycardia and vent ...
medication. Drugs.com: for hydroquinidine.


See also

* Dihydroquinine
Buchler_a_company_focussing_solely_on_cinchona_alkaloids_as_catalysts_such_as_Dihydroquinidine_or_Dihydroquinine
.html" ;"title="Dihydroquinine">Buchler a company focussing solely on cinchona alkaloids as catalysts such as Dihydroquinidine or Dihydroquinine
">Dihydroquinine">Buchler a company focussing solely on cinchona alkaloids as catalysts such as Dihydroquinidine or Dihydroquinine


References

{{Antiarrhythmic agents Secondary alcohols Phenol ethers Quinolines Quinuclidine alkaloids