Hydramethylnon is an
organofluorine compound. It is also known as AC 217,300. It is in a chemical class called trifluoromethyl amino
hydrazone
Hydrazones are a class of organic compounds with the structure . They are related to ketones and aldehydes by the replacement of the oxygen =O with the = functional group. They are formed usually by the action of hydrazine on ketones or aldehyde ...
, which is a
metabolic inhibitor. It is classified as a
pesticide designed to control insects that are harmful to humans.
It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of
oxidative phosphorylation. It is used primarily as an
insecticide in the form of
baits for
cockroach
Cockroaches (or roaches) are a Paraphyly, paraphyletic group of insects belonging to Blattodea, containing all members of the group except termites. About 30 cockroach species out of 4,600 are associated with human habitats. Some species are we ...
es and
ant
Ants are eusocial insects of the family Formicidae and, along with the related wasps and bees, belong to the order Hymenoptera. Ants evolved from vespoid wasp ancestors in the Cretaceous period. More than 13,800 of an estimated total of ...
s.
[Veterinary Support Personnel Network]
/ref> Some brands of insecticides that include hydramethylnon are Amdro
Amdro is a trade name for a hydramethylnon-based hydrazone insecticide, commonly used in the southern United States for fire ant control. Amdro was patented in 1978 by the American Cyanamid company, now Ambrands, and was conditionally approve ...
, Blatex, Combat, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.[
]
Toxicology
Hydramethylnon has low toxicity in mammals.[ Hydramethylnon is toxic to fish; the 96-hour LC50 in rainbow trout is 0.16 mg/L, 0.10 mg/L in channel catfish, and 1.70 mg/L in bluegill sunfish.
Hydramethylnon, when fed to rats for two years, led to an increase in ]uterine
The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The ...
and adrenal tumor
An adrenal tumor or adrenal mass is any benign or malignant neoplasms of the adrenal gland, several of which are notable for their tendency to overproduce endocrine hormones. Adrenal cancer is the presence of malignant adrenal tumors, and include ...
s at the highest dose; therefore, the Environmental Protection Agency classifies hydramethylnon as a possible human carcinogen.[
]
See also
* Fipronil, another insecticide used for similar purposes
References
External links
*
Hydramethylnon Technical Fact Sheet - National Pesticide Information CenterHydramethylnon General Fact Sheet - National Pesticide Information Center
* ttp://www.yorku.ca/dohs/documents/msds/MaxRoachSyringe_MSDS_E2024239.pdf MaxforceMSDS
A safety data sheet (SDS), material safety data sheet (MSDS), or product safety data sheet (PSDS) is a document that lists information relating to occupational safety and health for the use of various substances and products. SDSs are a widel ...
.
Amdro
MSDS
A safety data sheet (SDS), material safety data sheet (MSDS), or product safety data sheet (PSDS) is a document that lists information relating to occupational safety and health for the use of various substances and products. SDSs are a widel ...
{{Insecticides
Alkene derivatives
Benzene derivatives
Hydrazones
Insecticides
Trifluoromethyl compounds