Hyalobarrier is a substance to keep tissue apart post surgery and therefore prevent adhesions. It contains autocross-linked

hyaluronan Hyaluronic acid (; abbreviated HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans ...

. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural

metabolic pathway In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reac ...

for it. This gel is used to separate organs and tissue after surgery. Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery,

hysteroscopy Hysteroscopy is the inspection of the uterine cavity by endoscopy with access through the cervix. It allows for the diagnosis of intrauterine pathology and serves as a method for surgical intervention (operative hysteroscopy). Hysteroscope A hyst ...

/hysteroscopic surgery but also open surgery. According to data in a Cochrane collaboration review barrier agents may be a little more effective in preventing adhesions than no intervention. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 50 to 100%. In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use.

Additional information

* Laparoscopy *

Asherman's syndrome Asherman's syndrome (AS) is an acquired uterine condition that occurs when scar tissue (adhesions) forms inside the uterus and/or the cervix. It is characterized by variable scarring inside the uterine cavity, where in many cases the front and bac ...

References

* {{Medicine, date=June 2009 Biomaterials Implants (medicine) Medical equipment