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Huygens software refers to different
multiplatform In computing, cross-platform software (also called multi-platform software, platform-agnostic software, or platform-independent software) is computer software that is designed to work in several computing platforms. Some cross-platform software r ...
microscope image processing Microscope image processing is a broad term that covers the use of digital image processing techniques to process, analyze and present images obtained from a microscope. Such processing is now commonplace in a number of diverse fields such as medic ...
packages from Scientific Volume Imaging, made for restoring 2D and 3D
microscopy Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of micr ...
images or
time series In mathematics, a time series is a series of data points indexed (or listed or graphed) in time order. Most commonly, a time series is a sequence taken at successive equally spaced points in time. Thus it is a sequence of discrete-time data. Exa ...
and analyzing and visualizing them. The restoration is based on different
deconvolution In mathematics, deconvolution is the operation inverse to convolution. Both operations are used in signal processing and image processing. For example, it may be possible to recover the original signal after a filter (convolution) by using a deco ...
algorithm In mathematics and computer science, an algorithm () is a finite sequence of rigorous instructions, typically used to solve a class of specific Computational problem, problems or to perform a computation. Algorithms are used as specificat ...
s, that permit the recovery of objects from images that are degraded by blurring and noise. In
microscopy Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of micr ...
the blurring is largely due to
diffraction Diffraction is defined as the interference or bending of waves around the corners of an obstacle or through an aperture into the region of geometrical shadow of the obstacle/aperture. The diffracting object or aperture effectively becomes a s ...
limited imaging by the instrument; the
noise Noise is unwanted sound considered unpleasant, loud or disruptive to hearing. From a physics standpoint, there is no distinction between noise and desired sound, as both are vibrations through a medium, such as air or water. The difference arise ...
is usually
photon noise Photon noise is the randomness in signal associated with photons arriving at a detector. For a simple black body emitting on an absorber, the noise-equivalent power is given by :\mathrm^2 = 2 h^2 \nu^2 \Delta\nu \left( \frac + n^2 \right) where ...
. The
scientific visualization Scientific visualization ( also spelled scientific visualisation) is an interdisciplinary branch of science concerned with the visualization of scientific phenomena.Michael Friendly (2008)"Milestones in the history of thematic cartography, stat ...
of 3D volume data is based on the
simulated fluorescence process algorithm The Simulated Fluorescence Process (SFP) is a computing algorithm used for scientific visualization of 3D data from, for example, fluorescence microscopes. By modeling a physical light/matter interaction process, an image can be computed which sh ...
(SFP), but
isosurface An isosurface is a three-dimensional analog of an isoline. It is a surface that represents points of a constant value (e.g. pressure, temperature, velocity, density) within a volume of space; in other words, it is a level set of a continuous fu ...
s and
maximum intensity projection In scientific visualization, a maximum intensity projection (MIP) is a method for 3D data that projects in the visualization plane the voxels with maximum intensity that fall in the way of parallel rays traced from the viewpoint to the plane of ...
s are also used for object analysis and
colocalization In fluorescence microscopy, colocalization refers to observation of the spatial overlap between two (or more) different fluorescent labels, each having a separate emission wavelength, to see if the different "targets" are located in the same area of ...
. Huygens software is named after the Dutch physicist
Christiaan Huygens Christiaan Huygens, Lord of Zeelhem, ( , , ; also spelled Huyghens; la, Hugenius; 14 April 1629 – 8 July 1695) was a Dutch mathematician, physicist, engineer, astronomer, and inventor, who is regarded as one of the greatest scientists of ...
who is perhaps best known for his argument that light behaves like waves. Since wave diffraction plays a key role in the Huygens Software, it was named after him.


External links


Scientific Volume Imaging home pageSVI-wiki on 3D microscopy and deconvolution
{{graphics-software-stub Image processing software