The Disease Ontology (DO) is a formal
ontology of human
disease.
Th
Disease Ontology projectis hosted at th
Institute for Genome Sciencesat the
University of Maryland School of Medicine
The University of Maryland School of Medicine (abbreviated UMSOM), located in Baltimore City, Maryland, U.S., is the medical school of the University of Maryland, Baltimore and is affiliated with the University of Maryland Medical Center and Me ...
.
The Disease Ontology project was initially developed in 2003 at
Northwestern University to address the need for a purpose-built ontology that covers the full spectrum of disease concepts annotated within biomedical repositories within an ontological framework that is extensible to meet community needs.
The Disease Ontology is an OBO (
Open Biomedical Ontologies) Foundry ontology.
Disease Ontology Identifiers (DOIDs) consist of the prefix DOID: followed by number, for example,
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
has the stable identifie
DOID:10652 DO is cross-referenced in several resources such as
UniProt.
Example term
The Disease Ontology entry for
motor neuron disease in OBO format is given below, showing the links to other classification schemes, including
ICD-9,
ICD-10
ICD-10 is the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, ...
,
MeSH,
SNOMED and
UMLS.
:id: DOID:231
:name: motor neuron disease
:def: "A neurodegenerative disease that is located_in the motor neurones."
Motor neuron disease
:xref: ICD10CM:G12.2
:xref: ICD10CM:G12.20
:xref: ICD9CM:335.2
:xref: MSH:D016472
:xref: SNOMEDCT_US_2016_03_01:155015007
:xref: SNOMEDCT_US_2016_03_01:192888001
:xref: SNOMEDCT_US_2016_03_01:192889009
:xref: SNOMEDCT_US_2016_03_01:192890000
:xref: SNOMEDCT_US_2016_03_01:37340000
:xref: UMLS_CUI:C0085084
:is_a: DOID:1289 ! neurodegenerative disease
See also
Disease Ontology project*
References
{{reflist
External links
Disease Ontology web interfaceDO Wikisourceforge SVN trunkDO request trackerOBO Foundry
Ontology (information science)
Biological databases
Medical databases