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Cytomics is the study of
cell biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and ...
(
cytology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and ...
) and biochemistry in cellular systems at the single cell level.
It combines all the
bioinformatic
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combine ...
knowledge to attempt to understand the molecular architecture and functionality of the cell system (Cytome). Much of this is achieved by using
molecular
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
and
microscopic
The microscopic scale () is the scale of objects and events smaller than those that can easily be seen by the naked eye, requiring a lens (optics), lens or microscope to see them clearly. In physics, the microscopic scale is sometimes regarded a ...
techniques that allow the various components of a cell to be visualised as they interact ''
in vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and ...
''.
Cytome
Cytome
Cytomics is the study of cell biology (cytology) and biochemistry in cellular systems at the single cell level. It combines all the bioinformatic knowledge to attempt to understand the molecular architecture and functionality of the cell system (Cy ...
s are the cellular systems, subsystems, and functional components of the
body
Body may refer to:
In science
* Physical body, an object in physics that represents a large amount, has mass or takes up space
* Body (biology), the physical material of an organism
* Body plan, the physical features shared by a group of anima ...
. The cytome is the collection of the complex and dynamic cellular processes (structure and function) underlying
physiological
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
processes. It describes the structural and functional heterogeneity of the cellular diversity of an
organism
In biology, an organism () is any living system that functions as an individual entity. All organisms are composed of cells (cell theory). Organisms are classified by taxonomy into groups such as multicellular animals, plants, and ...
.
Human Cytome Project
The
Human Cytome Project
Cytomics is the study of cell biology (cytology) and biochemistry in cellular systems at the single cell level. It combines all the bioinformatic knowledge to attempt to understand the molecular architecture and functionality of the cell system (C ...
is aimed at the study of the biological system structure and function of an organism at the cytome level.
[Valet G., Predictive medicine by cytomics and the challenges of a human cytome project, Business Briefing: Future Drug Discovery 2004, Ed: E Cooper, World Markets Research Center Ltd, London, 2004; 46-51.]
See also
*
Flow cytometry
Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles.
In this process, a sample containing cells or particles is suspended in a fluid and injected into the flo ...
*
Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
*
Omics
The branches of science known informally as omics are various disciplines in biology whose names end in the suffix '' -omics'', such as genomics, proteomics, metabolomics, metagenomics, phenomics and transcriptomics. Omics aims at the collect ...
*
Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...
*
Lipidomics
Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems The word "lipidome" is used to describe the complete lipid profile within a cell, tissue, organism, or ecosystem and is a subset of the "metabolo ...
*
List of omics topics in biology
Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix '' -ome'' and ''-omics''. Some of these terms are related ...
*
Metabolomics
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprin ...
References
Further reading
* Bernas T., Gregori G., Asem E. K., Robinson J. P., Integrating cytomics and proteomics, Mol Cell Proteomics. 2006 Jan;5(1):2-13.
* Herrera G., Diaz L., Martinez-Romero A., Gomes A., Villamon E., Callaghan R. C., O'connor J. E., Cytomics: A multiparametric, dynamic approach to cell research, Toxicol In Vitro. 2006 Jul 22.
* Kriete A., Cytomics in the realm of systems biology, Cytometry A. 2005 Nov;68(1):19-20.
* Murphy R. F., Cytomics and location proteomics: automated interpretation of subcellular patterns in fluorescence microscope images, Cytometry A. 2005 Sep;67(1):1-3.
* Schubert W., Cytomics in characterizing toponomes: towards the biological code of the cell, Cytometry A. 2006 Apr;69(4):209-11.
* Van Osta P., Ver Donck K., Bols L., Geysen J., Cytomics and drug discovery., Cytometry A. 2006 Mar;69(3):117-8.
{{Genomics
Cell biology