Function
When inserted into liposomes and synthetic bilayers at low concentrations (2 nM), it provokes a cation-selective ion current with large unitary conductance. Chloride is not transported. It has been hypothesized that such channels could allow nutrient release and/or delivery of virulence factors during bacterial colonization of host plants. The leucine-zipper-like motifs may take part in the formation of oligomeric aggregates, and oligomerization could be related to HR elicitation.Transport reaction
The generalized transport reaction thought to be catalyzed by HrpZ is: :Small molecules (in) → Small molecules (out)References
Further reading
*{{cite journal , last1 = Chen , first1 = Jonathan S. , last2 = Reddy , first2 = Vamsee , last3 = Chen , first3 = Joshua H. , last4 = Shlykov , first4 = Maksim A. , last5 = Zheng , first5 = Wei Hao , last6 = Cho , first6 = Jaehoon , last7 = Yen , first7 = Ming Ren , last8 = Saier , first8 = Milton H. , year = 2011 , title = Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments , journal = Journal of Molecular Microbiology and Biotechnology , volume = 21 , issue = 3–4, pages = 83–96 , doi = 10.1159/000334611 , pmid = 22286036 , pmc = 3290041 Bacterial toxins