The Hounsfield scale , named after Sir
Godfrey Hounsfield
Sir Godfrey Newbold Hounsfield (28 August 1919 – 12 August 2004) was an English electrical engineer who shared the 1979 Nobel Prize for Physiology or Medicine with Allan MacLeod Cormack for his part in developing the diagnostic technique of X ...
, is a quantitative scale for describing
radiodensity
Radiodensity (or radiopacity) is opacity to the radio wave and X-ray portion of the electromagnetic spectrum: that is, the relative inability of those kinds of electromagnetic radiation to pass through a particular material. Radiolucency or hypod ...
. It is frequently used in
CT scans, where its value is also termed CT number.
Definition
The Hounsfield unit (HU) scale is a linear transformation of the original
linear attenuation coefficient
The linear attenuation coefficient, attenuation coefficient, or narrow-beam attenuation coefficient characterizes how easily a volume of material can be penetrated by a beam of light, sound, particles, or other energy or matter. A coefficient valu ...
measurement into one in which the
radiodensity
Radiodensity (or radiopacity) is opacity to the radio wave and X-ray portion of the electromagnetic spectrum: that is, the relative inability of those kinds of electromagnetic radiation to pass through a particular material. Radiolucency or hypod ...
of
distilled water
Distilled water is water that has been boiled into vapor and condensed back into liquid in a separate container. Impurities in the original water that do not boil below or near the boiling point of water remain in the original container. Thus, di ...
at standard
pressure
Pressure (symbol: ''p'' or ''P'') is the force applied perpendicular to the surface of an object per unit area over which that force is distributed. Gauge pressure (also spelled ''gage'' pressure)The preferred spelling varies by country and e ...
and
temperature
Temperature is a physical quantity that expresses quantitatively the perceptions of hotness and coldness. Temperature is measured with a thermometer.
Thermometers are calibrated in various temperature scales that historically have relied o ...
(
STP
STP may refer to:
Places
* São Tomé and Príncipe (ISO 3166-1 alpha-3 code, IOC country code, and FIFA country code STP)
* St Pancras railway station, London St Pancras (Domestic) railway station (National Rail code STP)
* St. Paul Downtown Air ...
) is defined as 0 Hounsfield units (HU), while the radiodensity of
air
The atmosphere of Earth is the layer of gases, known collectively as air, retained by Earth's gravity that surrounds the planet and forms its planetary atmosphere. The atmosphere of Earth protects life on Earth by creating pressure allowing for ...
at STP is defined as −1000 HU. In a
voxel
In 3D computer graphics, a voxel represents a value on a regular grid in three-dimensional space. As with pixels in a 2D bitmap, voxels themselves do not typically have their position (i.e. coordinates) explicitly encoded with their values. Ins ...
with average linear attenuation coefficient
, the corresponding HU value is therefore given by:
where
and
are respectively the linear attenuation coefficients of water and air.
Thus, a change of one Hounsfield unit (HU) represents a change of 0.1% of the attenuation coefficient of water since the attenuation coefficient of air is nearly zero.
Calibration tests of HU with reference to water and other materials may be done to ensure standardised response. This is particularly important for CT scans used in
radiotherapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radia ...
treatment planning
In radiotherapy, radiation treatment planning (RTP) is the process in which a team consisting of radiation oncologists, radiation therapist, medical physicists and medical dosimetrists plan the appropriate external beam radiotherapy or internal b ...
, where HU is converted to
electron density
In quantum chemistry, electron density or electronic density is the measure of the probability of an electron being present at an infinitesimal element of space surrounding any given point. It is a scalar quantity depending upon three spatial va ...
. Variation in the measured values of reference materials with known composition, and variation between and within slices may be used as part of test procedures.
Rationale
The above standards were chosen as they are universally available references and suited to the key application for which computed axial tomography was developed: imaging the internal anatomy of living creatures based on organized water structures and mostly living in air, ''e.g.''
human
Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, ...
s.
Values for different body tissues and material
HU-based differentiation of material applies to
medical-grade dual-energy CT scans but not to
cone beam computed tomography (CBCT) scans, as CBCT scans provide
unreliable HU readings.
Values reported here are approximations. Different dynamics are reported from one study to another.
Exact HU dynamics can vary from one CT acquisition to another due to CT acquisition and reconstruction parameters (kV, filters, reconstruction algorithms, etc.). The use of contrast agents modifies HU as well in some body parts (mainly blood).
A practical application of this is in evaluation of tumors, where, for example, an
adrenal tumor
An adrenal tumor or adrenal mass is any benign or malignant neoplasms of the adrenal gland, several of which are notable for their tendency to overproduce endocrine hormones. Adrenal cancer is the presence of malignant adrenal tumors, and includes ...
with a radiodensity of less than 10 HU is rather fatty in composition and almost certainly a benign
adrenal adenoma
Adrenocortical adenoma is commonly described as a benign neoplasm emerging from the cells that comprise the adrenal cortex. Like most adenomas, the adrenocortical adenoma is considered a benign tumor since the majority of them are non-functioning ...
.
medscape >Adrenal Adenoma Imaging
Author: Perry J Horwich. Chief Editor: Eugene C Lin. Updated: Apr 21, 2011
See also
* Cone beam computed tomography: Bone density and the Hounsfield scale.
References
*
External links
*
Hounsfield Unit
- fpnotebook.com
*{{cite web, url=http://www.intl.elsevierhealth.com/e-books/pdf/940.pdf, title=Introduction to CT physics, publisher=elsevierhealth.com, archive-url=https://web.archive.org/web/20070926231241/http://www.intl.elsevierhealth.com/e-books/pdf/940.pdf, archive-date=2007-09-26
Imaging of deep brain stimulation leads using extended Hounsfield unit CT. Stereotact Funct Neurosurg. 2009;87(3):155-60. doi: 10.1159/000209296
Radiology