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is a Japanese
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, thei ...
famous for his role in discovery of the anti-
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
drug
zidovudine Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child ...
(AZT) as well as other anti-AIDS drugs including
didanosine Didanosine (ddI, DDI), sold under the brand name Videx, is a medication used to treat HIV/AIDS. It is used in combination with other medications as part of highly active antiretroviral therapy (HAART). It is of the reverse-transcriptase inhibitor ...
(ddI) and
zalcitabine Zalcitabine (2′-3′-di deoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug ...
(ddC). Mitsuya was born in Sasebo, Nagasaki and received his M.D. and Ph.D. from
Kumamoto University , abbreviated to ''Kumadai'' (熊大), is a Japanese national university located in Kumamoto, Kumamoto Prefecture in the Kyushu region of Japan. It was established on May 31, 1949, at which time the following institutions were subsumed into it; ...
. He joined the American
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
in
Bethesda, Maryland Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland. It is located just northwest of Washington, D.C. It takes its name from a local church, the Bethesda Meeting House (1820, rebuilt 1849), which in ...
, in 1982, working initially on
Human T-lymphotropic virus 1 Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus (HTLV-I), also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseas ...
before switching his attention to
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
. His identification of AZT as an anti-HIV drug, as well as the anti-HIV properties of
didanosine Didanosine (ddI, DDI), sold under the brand name Videx, is a medication used to treat HIV/AIDS. It is used in combination with other medications as part of highly active antiretroviral therapy (HAART). It is of the reverse-transcriptase inhibitor ...
and
zalcitabine Zalcitabine (2′-3′-di deoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug ...
, was made in 1985. He was appointed Professor of Hematology, Rheumatology and Clinical Immunology at
Kumamoto University , abbreviated to ''Kumadai'' (熊大), is a Japanese national university located in Kumamoto, Kumamoto Prefecture in the Kyushu region of Japan. It was established on May 31, 1949, at which time the following institutions were subsumed into it; ...
Graduate School of Medical And Pharmaceutical Sciences. In December, 2006, he was awarded the first
NIH The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
World AIDS Day Award for his work in developing drugs for AIDS. Mitsuya has been chief of the NCI's Experimental Retrovirology Section since 1991.


References and Links

*
Page describing Dr. Mitsuya's research on NCI website
* Yarchoan R, Mitsuya H, Broder S. AIDS therapies. Scientific American 1988;259(4):110-9 1950 births Living people Japanese virologists HIV/AIDS researchers People from Sasebo Kumamoto University alumni Kumamoto University faculty {{japan-scientist-stub