Herman Waldmann
FRS FMedSci (born 27 February 1945) is a British
immunologist known for his work on therapeutic
monoclonal antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
Monoclonal antibodies ca ...
. As of 2013, he is Emeritus Professor of Pathology at the Sir William Dunn School of Pathology at the
University of Oxford.
Career and research
Waldmann grew up in north-east London, and was a student at the
Sir George Monoux Grammar School
''Sir'' is a formal honorific address in English for men, derived from Sire in the High Middle Ages. Both are derived from the old French "Sieur" (Lord), brought to England by the French-speaking Normans, and which now exist in French only as ...
,
Walthamstow
Walthamstow ( or ) is a large town in East London, east London, England, within the Ceremonial counties of England, ceremonial county of Greater London and the Historic counties of England, ancient county of Essex. Situated northeast of Chari ...
and
Sidney Sussex College, Cambridge
Sidney Sussex College (referred to informally as "Sidney") is a constituent college of the University of Cambridge in England. The College was founded in 1596 under the terms of the will of Frances Sidney, Countess of Sussex (1531–1589), wife ...
. He worked in the Department of Pathology of the
University of Cambridge from 1973, becoming head of the Immunology Division in 1989. In 1994, he took up the position of head of the Sir William Dunn School of Pathology at the
University of Oxford. He is a fellow of
Lincoln College.
Waldmann's research has focused on
immunological tolerance
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that would otherwise have the capacity to elicit an immune response in a given organism. It is induced by ...
and the harnessing of tolerance mechanisms to treat autoimmune diseases and enable transplant acceptance. He is best known for his work on therapeutic
monoclonal antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
Monoclonal antibodies ca ...
and their use to achieve tolerance, particularly Campath-1, now licensed as Lemtrada for the treatment of Multiple Sclerosis.
Awards and honours
Waldmann was elected a Fellow of the
Royal Society in 1990. He delivered the 1992
Bradshaw Lecture at the Royal College of Physicians. In 1998, he was a founding fellow of the
Academy of Medical Sciences. In 2008, he was awarded an honorary doctorate ScD(Hon) by the University of Cambridge. In 2010 he became a Fellow of the Royal College of Physicians (FRCP). In 2005 he received the Jose Carreras award from the European Hematology Association and also, the Excellence in Clinical Research Award from the Juvenile Diabetes Research Foundation. In 2007 he was awarded Thomas E Starzl Prize in Surgery and Immunology, and also, the Scrip Lifetime Achievement award from the Pharmaceutical industry. He is an honorary fellow of Queen Mary Westfield College, and of both King's College and Sidney Sussex College, Cambridge.
He is an honorary member of the
British Society for Immunology.
References
External links
Biography at ISI Highly Cited Researchers€”photo, links to CV & publications list
From laboratory to clinic: the story of CAMPATH-1 (Geoff Hale and Herman Waldmann)
{{DEFAULTSORT:Waldmann, Herman
1945 births
Living people
Alumni of Sidney Sussex College, Cambridge
British immunologists
Fellows of the Royal Society
Fellows of the Academy of Medical Sciences (United Kingdom)
Fellows of Lincoln College, Oxford
Statutory Professors of the University of Oxford