Herbert Wilson (other)
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Herbert Rees Wilson
FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This soci ...
(20 March 1929 – 22 May 2008) was a physicist, who was one of the team who worked on the structure of DNA at
King's College London King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's ...
, under the direction of Sir John Randall.


Biography


Early life

He was born the son of a sea captain at Nefyn on the Llŷn Peninsula and educated at Nefyn school and Pwllheli Grammar School. He entered
Bangor University , former_names = University College of North Wales (1884–1996) University of Wales, Bangor (1996–2007) , image = File:Arms_of_Bangor_University.svg , image_size = 250px , caption = Arms ...
, where he gained a first class honours degree in physics in 1949 and a PhD in 1952 under the supervision of professor Edwin Owen.


College education

Having received a University of Wales fellowship, Wilson joined
Maurice Wilkins Maurice Hugh Frederick Wilkins (15 December 1916 – 5 October 2004) was a New Zealand-born British biophysicist and Nobel laureate whose research spanned multiple areas of physics and biophysics, contributing to the scientific understanding o ...
at
King's College London King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's ...
in September 1952. The work involved
X-ray diffraction X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles ...
studies of DNA, nucleoproteins and cell nuclei. Prior to the double helix model, their studies showed that DNAs from different sources (including biologically active transforming principle) had essentially the same structure, and confirmed that the phosphate groups were on the outside of the molecule.


Scientific discoveries and achievements

Three papers were published in Nature, April 1953, to announce a structure for DNA. Maurice Wilkins,
Alex Stokes Alexander Rawson Stokes (27 June 1919 – 6 February 2003) was a British physicist at Royal Holloway College, London and later at King's College London. He was most recognised as a co-author of the second of the three papers published sequenti ...
and Wilson published their paper in the same issue as the paper from
Rosalind Franklin Rosalind Elsie Franklin (25 July 192016 April 1958) was a British chemist and X-ray crystallographer whose work was central to the understanding of the molecular structures of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), viruses, co ...
and Raymond Gosling, and the paper by
Francis Crick Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical struc ...
and
James Watson James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and ...
. The 1962 Nobel Prize for Physiology or Medicine was subsequently jointly awarded to Francis Crick, James Watson, and Maurice Wilkins. In his autobiography ''The Third Man of The Double Helix'', Maurice Wilkins does not specifically credit Stokes, Wilson and several other co-authors of his papers in ''Nature''. Whether this was deliberate on his part or just rather poor sub-editing by OUP is debatable. It is most likely to have been a matter of expedience, as there were more than five co-authors on several of his later papers on the subject published in ''Nature'' or, later, in the ''Journal of Molecular Biology''. Nevertheless, both he and Alex Stokes are now recognized at
King's College King's College or The King's College refers to two higher education institutions in the United Kingdom: *King's College, Cambridge, a constituent of the University of Cambridge *King's College London, a constituent of the University of London It ca ...
as two of the eight key researchers that contributed to the discovery of the structure of the A-DNA crystalline structure. Following the publication of the double helical structure in 1953, Wilson participated in the refinement of the DNA structure in Wilkins' group. In 1957 Professor Wilson was appointed Lecturer in Physics at Queen's College, Dundee, then at University of St Andrews, became a Senior Lecturer in 1964, and then Reader at the University of Dundee in 1973. In 1962 he was Visiting Research Associate at the Children's Cancer Research Foundation, Boston Mass. In 1983 he was appointed Professor of Physics at the University of Stirling from which he retired as Emeritus Professor in 1994. His research at Dundee and Stirling has involved X-ray crystallographic studies of nucleic acid components and their analogues, and structural studies of flexuous viruses. He was awarded an Honorary Fellowship by the
University of Wales, Bangor Bangor University ( cy, Prifysgol Bangor) is a Public university, public university in Bangor, Gwynedd, Bangor, Wales. It received its Royal charter, Royal Charter in 1885 and was one of the founding institutions of the federal University of Wales ...
in 2005. In 1975 he was elected a Fellow of the Royal Society of Edinburgh. As a Welshman Herbert was honoured in 2003 at the
National Eisteddfod The National Eisteddfod of Wales (Welsh: ') is the largest of several eisteddfodau that are held annually, mostly in Wales. Its eight days of competitions and performances are considered the largest music and poetry festival in Europe. Competitors ...
in Wales by being given the official white robe of the Gorsedd of Bards. After suffering from terminal cancer, Wilson died on 22 May 2008. He was survived by his wife, two daughters, and two grandchildren; his son Neil predeceased him in 1996.


Books and articles by Herbert R. Wilson, FRS


Books

*Herbert R. Wilson. 1966. ''Diffraction of X-rays by Proteins, Nucleic Acids and Viruses.'',Cited in a recently contributed book: ''Mathematical and Experimental Biophysicists: Biographies and Related Fields'', (Bci2, ed.), pp.382, 31 January 2010, v.7. in Wikipedia London: Arnold publs.


Original articles

* Wilkins, M.H.F., Stokes, A.R. and H.R. Wilson.(1953). ''Nature'', 171, 737. * Wilkins, M.H.F., Seeds, W.E., Stokes, A.R. and H.R. Wilson.(1953). ''Nature'', 171, 759. * Wilkins, M.H.F., Zubay, G. and H.R. Wilson. (1959). ''J. Mol. Biol''., 1, 179. * H.R. Wilson. (with Feughelman, M., & Langridge, R. ''et al.'').(1955). ''Nature'', 175, 834. * H.R. Wilson. (with Langridge, R. ''et al.''). (1960). ''J. Mol. Biol.'', 2, 19. * H.R. Wilson. (with Langridge, R, ''et al.''). (1960). ''J. Mol. Biol.'', 2, 38. * H.R. Wilson. (with Fuller, W. ''et al.''). (1965). ''J. Mol. Biol.'', 12, 60.


Books featuring Herbert R. Wilson

* Chomet, S. (Ed.), ''D.N.A. Genesis of a Discovery'', 1994, Newman- Hemisphere Press, London; NB a few copies are available from Newman-Hemisphere at 101 Swan Court, London SW3 5RY. * Wilkins, Maurice, The Third Man of the Double Helix: The Autobiography of Maurice Wilkins . * Ridley, Matt; "Francis Crick: Discoverer of the Genetic Code (Eminent Lives)" was first published in June 2006 in the US and then in the UK September 2006, by HarperCollins Publishers; 192 pp, . his short book is in the publisher's "Eminent Lives" series.* Contributed book: ''Mathematical and Experimental Biophysicists: Biographies and Related Fields'', (Bci2, ed.), pp. 382, 31 January 2010, v.7. in Wikipedia * Tait, Sylvia & James "A Quartet of Unlikely Discoveries" (Athena Press 2004)


Notes


External links


King's College London link

Photos at 40th anniversary
(From left: Raymond Gosling, Herbert Wilson, Maurice Wilkins and Alec Stokes)

{{DEFAULTSORT:Wilson, Herbert Rees 1929 births 2008 deaths Alumni of Bangor University Academics of King's College London Academics of the University of Wales Academics of the University of St Andrews Academics of the University of Dundee Academics of the University of Stirling British physicists Fellows of the Royal Society of Edinburgh People from Pwllheli