The Hepatitis C stem-loop IV is part of a putative
RNA element found in the
NS5B
Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). It is an RNA-dependent RNA polymerase, having the key function of replicating HCV's viral RNA by using the viral positive RNA strand as a template to catalyze ...
coding region. This element along with
stem-loop VII, is important (but not essential) for colony formation, though its exact function and mechanism are unknown.
See also
*
Hepatitis C alternative reading frame stem-loop
Hepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating Translation (biology), translation and r ...
*
Hepatitis C virus (HCV) cis-acting replication element (CRE)
The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and i ...
*
Hepatitis C virus 3'X element
The hepatitis C virus 3′X element is an RNA element which contains three stem-loop structures that are essential for replication.
See also
* Hepatitis C alternative reading frame stem-loop
* Hepatitis C stem-loop IV
* Hepatitis C virus ste ...
*
Hepatitis E virus cis-reactive element
The hepatitis E virus cis-reactive element is an RNA element that is believed to be essential for "some step in gene expression". The mutation of this element resulted in hepatitis E strains which were unable to infect rhesus macaque
The rhesu ...
References
External links
*
Cis-regulatory RNA elements
Hepatitis C virus
{{molecular-cell-biology-stub